Calibrated comparison of SARS-CoV-2 neutralizing antibody levels in response to protein-, mRNA-, and vector-based COVID-19 vaccines.
Journal
NPJ vaccines
ISSN: 2059-0105
Titre abrégé: NPJ Vaccines
Pays: England
ID NLM: 101699863
Informations de publication
Date de publication:
18 Feb 2022
18 Feb 2022
Historique:
received:
23
12
2021
accepted:
31
01
2022
entrez:
19
2
2022
pubmed:
20
2
2022
medline:
20
2
2022
Statut:
epublish
Résumé
SARS-CoV-2 neutralizing antibodies have been suggested to reflect the efficacy of COVID-19 vaccines. This study reports the direct comparison of the SARS-CoV-2 neutralizing antibody response elicited by a protein- (NVX-CoV2373), an mRNA- (Comirnaty), and a vector-based (Vaxzevria) COVID-19 vaccine, calibrated against the WHO international SARS-CoV-2 antibody standard, and further supports the use of neutralizing antibody levels as a correlate of protection.
Identifiants
pubmed: 35181655
doi: 10.1038/s41541-022-00455-3
pii: 10.1038/s41541-022-00455-3
pmc: PMC8857217
doi:
Types de publication
Journal Article
Langues
eng
Pagination
22Informations de copyright
© 2022. The Author(s).
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