The Guide to Dendritic Spikes of the Mammalian Cortex In Vitro and In Vivo.
dendritic action potentials
dendritic computation
dendritic electrophysiology
dendritic spikes
Journal
Neuroscience
ISSN: 1873-7544
Titre abrégé: Neuroscience
Pays: United States
ID NLM: 7605074
Informations de publication
Date de publication:
01 05 2022
01 05 2022
Historique:
received:
17
03
2021
revised:
01
02
2022
accepted:
10
02
2022
pubmed:
20
2
2022
medline:
27
4
2022
entrez:
19
2
2022
Statut:
ppublish
Résumé
Half a century since their discovery by Llinás and colleagues, dendritic spikes have been observed in various neurons in different brain regions, from the neocortex and cerebellum to the basal ganglia. Dendrites exhibit a terrifically diverse but stereotypical repertoire of spikes, sometimes specific to subregions of the dendrite. Despite their prevalence, we only have a glimpse into their role in the behaving animal. This article aims to survey the full range of dendritic spikes found in excitatory and inhibitory neurons, compare themin vivoversusin vitro, and discuss new studies describing dendritic spikes in the human cortex. We focus on neocortical and hippocampal neurons and present a roadmap to identify and understand the broader role of dendritic spikes in single-cell computation.
Identifiants
pubmed: 35182699
pii: S0306-4522(22)00063-X
doi: 10.1016/j.neuroscience.2022.02.009
pii:
doi:
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
15-33Informations de copyright
Copyright © 2022 IBRO. Published by Elsevier Ltd.. All rights reserved.