Perceptual hue, lightness, and chroma are represented in a multidimensional functional anatomical map in macaque V1.
Color perception
Functional map
Macaque
Primary visual cortex
Two-photon imaging
Journal
Progress in neurobiology
ISSN: 1873-5118
Titre abrégé: Prog Neurobiol
Pays: England
ID NLM: 0370121
Informations de publication
Date de publication:
05 2022
05 2022
Historique:
received:
26
09
2021
revised:
02
02
2022
accepted:
12
02
2022
pubmed:
20
2
2022
medline:
6
5
2022
entrez:
19
2
2022
Statut:
ppublish
Résumé
Humans perceive millions of colors along three dimensions of color space: hue, lightness, and chroma. A major gap in knowledge is where the brain represents these specific dimensions in cortex, and how they relate to each other. Previous studies have shown that brain areas V4 and the posterior inferotemporal cortex (PIT) are central to computing color dimensions. To determine the contribution of V1 to setting up these downstream processing mechanisms, we studied cortical color responses in macaques-who share color vision mechanisms with humans. We used two-photon calcium imaging at both meso- and micro-scales and found that hue and lightness are laid out in orthogonal directions on the cortical map, with chroma represented by the strength of neuronal responses, as previously shown in PIT. These findings suggest that the earliest cortical stages of vision determine the three primary dimensions of human color perception.
Identifiants
pubmed: 35182707
pii: S0301-0082(22)00037-5
doi: 10.1016/j.pneurobio.2022.102251
pmc: PMC9392963
mid: NIHMS1827798
pii:
doi:
Substances chimiques
Calcium
SY7Q814VUP
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
102251Subventions
Organisme : NCI NIH HHS
ID : R01 CA258021
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY031971
Pays : United States
Informations de copyright
Copyright © 2022 Elsevier Ltd. All rights reserved.
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