Animated, video entertainment-education to improve vaccine confidence globally during the COVID-19 pandemic: an online randomized controlled experiment with 24,000 participants.

COVID-19 Hope List experiment Protocol Rrandomized controlled trial Vaccine acceptance Vaccine confidence Vaccine hesitancy

Journal

Trials
ISSN: 1745-6215
Titre abrégé: Trials
Pays: England
ID NLM: 101263253

Informations de publication

Date de publication:
19 Feb 2022
Historique:
received: 17 04 2021
accepted: 29 01 2022
entrez: 20 2 2022
pubmed: 21 2 2022
medline: 23 2 2022
Statut: epublish

Résumé

Science-driven storytelling and entertainment-education (E-E) media demonstrate potential for promoting improved attitudes and behavioral intent towards health-related practices. Months after the outbreak of coronavirus disease 2019 (COVID-19), emerging research highlights the essential role of interventions to improve public confidence in the COVID-19 vaccine. To improve vaccine confidence, we designed three short, animated videos employing three research-informed pedagogical strategies. These can be distributed globally through social media platforms, because of their wordless and culturally accessible design. However, the effectiveness of short, animated storytelling videos, deploying various pedagogic strategies, needs to be explored across different global regions. The present study is a multi-site, parallel group, randomized controlled trial (RCT) comparing the effectiveness of (i) a storytelling-instructional-humor approach, (ii) a storytelling-analogy approach, (iii) a storytelling-emotion-focused approach, and (iv) no video. For our primary outcomes, we will measure vaccine hesitancy, and for secondary outcomes, we will measure behavioral intent to seek vaccination and hope. Using online platforms, we will recruit 12,000 participants (aged 18-59 years) from the USA and China, respectively, yielding a total sample size of 24,000. This trial uses innovative online technology, reliable randomization algorithms, validated survey instruments, and list experiments to establish the effectiveness of three short, animated videos employing various research-informed pedagogical strategies. Results will be used to scientifically support the broader distribution of these short, animated video as well as informing the design of future videos for rapid, global public health communication. German Clinical Trials Register DRKS #00023650 . Date of registration: 2021/02/09.

Sections du résumé

BACKGROUND BACKGROUND
Science-driven storytelling and entertainment-education (E-E) media demonstrate potential for promoting improved attitudes and behavioral intent towards health-related practices. Months after the outbreak of coronavirus disease 2019 (COVID-19), emerging research highlights the essential role of interventions to improve public confidence in the COVID-19 vaccine. To improve vaccine confidence, we designed three short, animated videos employing three research-informed pedagogical strategies. These can be distributed globally through social media platforms, because of their wordless and culturally accessible design. However, the effectiveness of short, animated storytelling videos, deploying various pedagogic strategies, needs to be explored across different global regions.
METHODS/DESIGN METHODS
The present study is a multi-site, parallel group, randomized controlled trial (RCT) comparing the effectiveness of (i) a storytelling-instructional-humor approach, (ii) a storytelling-analogy approach, (iii) a storytelling-emotion-focused approach, and (iv) no video. For our primary outcomes, we will measure vaccine hesitancy, and for secondary outcomes, we will measure behavioral intent to seek vaccination and hope. Using online platforms, we will recruit 12,000 participants (aged 18-59 years) from the USA and China, respectively, yielding a total sample size of 24,000.
DISCUSSION CONCLUSIONS
This trial uses innovative online technology, reliable randomization algorithms, validated survey instruments, and list experiments to establish the effectiveness of three short, animated videos employing various research-informed pedagogical strategies. Results will be used to scientifically support the broader distribution of these short, animated video as well as informing the design of future videos for rapid, global public health communication.
TRIAL REGISTRATION BACKGROUND
German Clinical Trials Register DRKS #00023650 . Date of registration: 2021/02/09.

Identifiants

pubmed: 35183238
doi: 10.1186/s13063-022-06067-5
pii: 10.1186/s13063-022-06067-5
pmc: PMC8857749
doi:

Substances chimiques

Vaccines 0

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Pagination

161

Subventions

Organisme : Chinesisch-Deutsche Zentrum für Wissenschaftsförderung
ID : Project C-0048
Organisme : Chinesisch-Deutsche Zentrum für Wissenschaftsförderung
ID : Project C-0048
Organisme : Chinesisch-Deutsche Zentrum für Wissenschaftsförderung
ID : Project C-0048
Organisme : Chinesisch-Deutsche Zentrum für Wissenschaftsförderung
ID : Project C-0048
Organisme : Chinesisch-Deutsche Zentrum für Wissenschaftsförderung
ID : Project C-0048
Organisme : Chinesisch-Deutsche Zentrum für Wissenschaftsförderung
ID : Project C-0048
Organisme : Chinesisch-Deutsche Zentrum für Wissenschaftsförderung
ID : Project C-0048

Informations de copyright

© 2022. The Author(s).

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Auteurs

Simiao Chen (S)

Heidelberg Institute of Global Health (HIGH), Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, Germany. simiao.chen@uni-heidelberg.de.
Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. simiao.chen@uni-heidelberg.de.

Sebastian Forster (S)

Heidelberg Institute of Global Health (HIGH), Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, Germany.

Juntao Yang (J)

State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

Fengyun Yu (F)

Department of Industrial Engineering, Tsinghua University, Beijing, China.

Lirui Jiao (L)

Reed College, Portland, OR, USA.

Jennifer Gates (J)

Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Zhuoran Wang (Z)

Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Haitao Liu (H)

Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Qiushi Chen (Q)

The Harold and Inge Marcus Department of Industrial and Manufacturing Engineering, The Pennsylvania State University, University Park, PA, USA.

Pascal Geldsetzer (P)

Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.

Peixin Wu (P)

Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Peking Union Medical College Hospital, Beijing, China.

Chen Wang (C)

Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
National Clinical Research Center for Respiratory Diseases, Beijing, China.
Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China.

Shannon McMahon (S)

Heidelberg Institute of Global Health (HIGH), Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, Germany.

Till Bärnighausen (T)

Heidelberg Institute of Global Health (HIGH), Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, Germany.
Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Africa Health Research Institute (AHRI), Somkhele, KwaZulu-Natal, South Africa.

Maya Adam (M)

Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.

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Classifications MeSH