Health-related quality of life of COVID-19 two and 12 months after intensive care unit admission.
Acute respiratory distress syndrome
COVID-19
Dyspnea
Exercise capacity
Health-related quality of life
Mechanical ventilation
Mortality
Pulmonary function tests
Six-minute walk test
Journal
Annals of intensive care
ISSN: 2110-5820
Titre abrégé: Ann Intensive Care
Pays: Germany
ID NLM: 101562873
Informations de publication
Date de publication:
20 Feb 2022
20 Feb 2022
Historique:
received:
23
09
2021
accepted:
04
02
2022
entrez:
20
2
2022
pubmed:
21
2
2022
medline:
21
2
2022
Statut:
epublish
Résumé
To describe health-related quality of life (HRQoL) and dyspnea of COVID-19, 2 and 12 months after an intensive care unit (ICU) stay. Patients discharged from the ICU between April and June 2020 and subsequently transferred to an inpatient rehabilitation facility were assessed 2 months and 12 months after ICU admission. HRQoL was assessed by the EuroQoL EQ-5D-3L (visual analog scale and time trade-off normalized to the French population algorithm) and dyspnea was assessed by the modified Medical Research Council (mMRC) dyspnea scale. We enrolled 94 patients. Median EQ-5D-3L time trade-off was 0.80 (interquartile range, 0.36-0.91) at 2 months and 0.91 (0.52-1.00) at 12 months (P = 0.12). EQ-5D-3L visual analog scale was 70 (60-85) at 2 months and 70 (60-85) at 12 months (P = 0.07). The mMRC dyspnea scale was 3 (2-4) at ICU discharge, 1 (0-2), P < 0.001 at 2 months and 1 (1-2) at 12 months. At 12 months, 68 (76%) patients reported at least one symptom that was not present prior to ICU admission and 27 (61%) of the 44 patients who were previously working had returned to work. On multiple linear regression, factors associated with EQ-5D-3L were body mass index on ICU admission, tracheostomy, male gender and active smoking. Twelve months after ICU admission for COVID-19 and subsequent rehabilitation, a substantial proportion of patients reported alterations of HRQoL, dyspnea and symptoms that were not present prior to admission and a substantial proportion of these patients had not returned to work. Factors associated with a risk of poorer 12-month quality of life, may help to identify at-risk patients.
Identifiants
pubmed: 35184214
doi: 10.1186/s13613-022-00991-0
pii: 10.1186/s13613-022-00991-0
pmc: PMC8858438
doi:
Types de publication
Journal Article
Langues
eng
Pagination
16Informations de copyright
© 2022. The Author(s).
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