Sleep Apnea Syndrome: Prevalence and Comorbidity with Other Non-communicable Diseases and HIV Infection, among Hospitalized Patients in Yaoundé, Cameroon.


Journal

Sleep disorders
ISSN: 2090-3545
Titre abrégé: Sleep Disord
Pays: United States
ID NLM: 101600304

Informations de publication

Date de publication:
2022
Historique:
received: 22 10 2021
revised: 28 12 2021
accepted: 07 01 2022
entrez: 21 2 2022
pubmed: 22 2 2022
medline: 22 2 2022
Statut: epublish

Résumé

Sleep apnea syndrome (SAS), a growing public health threat, is an emerging condition in sub-Saharan Africa (SSA). Related SSA studies have so far used an incomplete definition. This study is aimed at assessing SAS using an American Academy of Sleep Medicine (AASM) complete definition and at exploring its relationship with comorbidities, among patients hospitalized in a Cameroonian tertiary hospital. This cross-sectional study was conducted in cardiology, endocrinology, and neurology departments of the Yaoundé Central Hospital. Patients aged 21 and above were consecutively invited, and some of them were randomly selected to undergo a full night record using a portable sleep monitoring device, to diagnose sleep-disordered breathing (SDB). SAS was defined as an apnea - hypopnea index (AHI) ≥ 5/h, associated with either excessive daytime sleepiness or at least 3 compatible symptoms. Moderate to severe SAS (MS-SAS) stood for an AHI ≥ 15/h. We used chi-square or Fisher tests to compare SAS and non-SAS groups. The SAS diagnosed using modified AASM definition showed high prevalence among patients hospitalized for acute medical conditions, as it was found with SDB. Unlike HIV infection, metabolic and brain conditions, cardiovascular comorbidities (hypertension and cardiac failure) were significantly more prevalent in SAS patients.

Sections du résumé

BACKGROUND BACKGROUND
Sleep apnea syndrome (SAS), a growing public health threat, is an emerging condition in sub-Saharan Africa (SSA). Related SSA studies have so far used an incomplete definition. This study is aimed at assessing SAS using an American Academy of Sleep Medicine (AASM) complete definition and at exploring its relationship with comorbidities, among patients hospitalized in a Cameroonian tertiary hospital.
METHODS METHODS
This cross-sectional study was conducted in cardiology, endocrinology, and neurology departments of the Yaoundé Central Hospital. Patients aged 21 and above were consecutively invited, and some of them were randomly selected to undergo a full night record using a portable sleep monitoring device, to diagnose sleep-disordered breathing (SDB). SAS was defined as an apnea - hypopnea index (AHI) ≥ 5/h, associated with either excessive daytime sleepiness or at least 3 compatible symptoms. Moderate to severe SAS (MS-SAS) stood for an AHI ≥ 15/h. We used chi-square or Fisher tests to compare SAS and non-SAS groups.
CONCLUSION CONCLUSIONS
The SAS diagnosed using modified AASM definition showed high prevalence among patients hospitalized for acute medical conditions, as it was found with SDB. Unlike HIV infection, metabolic and brain conditions, cardiovascular comorbidities (hypertension and cardiac failure) were significantly more prevalent in SAS patients.

Identifiants

pubmed: 35186334
doi: 10.1155/2022/4359294
pmc: PMC8853793
doi:

Types de publication

Journal Article

Langues

eng

Pagination

4359294

Informations de copyright

Copyright © 2022 Massongo Massongo et al.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest related to this study.

Références

Am J Respir Crit Care Med. 2001 Jan;163(1):19-25
pubmed: 11208620
BMC Cardiovasc Disord. 2017 May 8;17(1):112
pubmed: 28482815
J Physiol Pharmacol. 2009 Nov;60 Suppl 5:45-9
pubmed: 20134038
J Assoc Nurses AIDS Care. 2013 Jan-Feb;24(1 Suppl):S72-85
pubmed: 23290379
Lancet. 2005 Mar 19-25;365(9464):1046-53
pubmed: 15781100
BMC Nephrol. 2017 Oct 16;18(1):313
pubmed: 29037156
J Diabetes. 2015 Jan;7(1):16-23
pubmed: 24910109
PLoS One. 2020 Jan 16;15(1):e0227778
pubmed: 31945127
Chest. 2017 Nov;152(5):1070-1086
pubmed: 28527878
Proc Am Thorac Soc. 2008 Feb 15;5(2):136-43
pubmed: 18250205
Sleep. 2000 Jun 15;23 Suppl 4:S122-6
pubmed: 10893084
N Engl J Med. 2005 Nov 10;353(19):2034-41
pubmed: 16282178
Am J Respir Crit Care Med. 1999 Oct;160(4):1101-6
pubmed: 10508793
J Res Med Sci. 2014 Mar;19(3):205-10
pubmed: 24949026
Int J STD AIDS. 2006 Sep;17(9):614-20
pubmed: 16942653
Arch Intern Med. 2006 May 22;166(10):1092-7
pubmed: 16717171
Niger Med J. 2014 Jan;55(1):24-8
pubmed: 24970965
Pan Afr Med J. 2014 Apr 21;17:302
pubmed: 25328598
Am J Respir Crit Care Med. 1995 May;151(5):1459-65
pubmed: 7735600
Chest. 2014 Oct;146(4):982-990
pubmed: 24831859
PLoS One. 2010 Apr 16;5(4):e10211
pubmed: 20419135
Am J Respir Crit Care Med. 2004 Nov 15;170(10):1108-13
pubmed: 15347562
JAMA. 1999 Nov 10;282(18):1737-44
pubmed: 10568646
Am J Respir Crit Care Med. 2001 Mar;163(3 Pt 1):608-13
pubmed: 11254512
N Engl J Med. 1993 Apr 29;328(17):1230-5
pubmed: 8464434
JAMA. 2000 Apr 12;283(14):1829-36
pubmed: 10770144
Eur Arch Otorhinolaryngol. 2012 Dec;269(12):2549-53
pubmed: 22298252
Can J Cardiol. 2015 Jul;31(7):918-27
pubmed: 26112302
Am J Respir Crit Care Med. 2004 Jan 15;169(2):168-73
pubmed: 14604837
Sleep. 1999 Mar 15;22(2):217-23
pubmed: 10201066
PLoS Med. 2009 Aug;6(8):e1000132
pubmed: 19688045
Ann Cardiol Angeiol (Paris). 2014 Apr;63(2):65-70
pubmed: 24485826
BMC Pulm Med. 2015 Sep 21;15:105
pubmed: 26391008
Lancet Respir Med. 2016 May;4(5):e19-20
pubmed: 27304561
Lancet Respir Med. 2019 Aug;7(8):687-698
pubmed: 31300334
Sleep. 2008 Aug;31(8):1071-8
pubmed: 18714778
Arch Med Sci. 2016 Oct 1;12(5):1077-1087
pubmed: 27695500
Lancet. 1998 Mar 21;351(9106):867-70
pubmed: 9525364
J Cardiometab Syndr. 2008 Spring;3(2):111-4
pubmed: 18453812
Circulation. 2010 Jul 27;122(4):352-60
pubmed: 20625114
Lancet Respir Med. 2016 Feb;4(2):e5-6
pubmed: 26868630
J Appl Physiol (1985). 2005 Nov;99(5):1998-2007
pubmed: 16227461
Am J Respir Crit Care Med. 2010 Jul 15;182(2):269-77
pubmed: 20339144
Sleep. 1999 Aug 1;22(5):667-89
pubmed: 10450601
J Clin Sleep Med. 2016 Jan;12(1):105-12
pubmed: 26350608
JAMA. 2012 May 23;307(20):2169-76
pubmed: 22618924
Chest. 2004 Jan;125(1):127-34
pubmed: 14718431
Niger Med J. 2013 Jul;54(4):224-9
pubmed: 24249946
Lancet Respir Med. 2015 Apr;3(4):310-8
pubmed: 25682233
Braz J Otorhinolaryngol. 2012 Dec;78(6):27-33
pubmed: 23306564
Sleep Breath. 2013 Mar;17(1):343-50
pubmed: 22467194
Chest. 2001 Jan;119(1):62-9
pubmed: 11157585

Auteurs

Massongo Massongo (M)

Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.
Pulmonology Department, Yaoundé Jamot Hospital, Yaoundé, Cameroon.

Leonard Ngarka (L)

Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.
Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon.
Brain Research Africa Initiative (BRAIN), Geneva, Switzerland.

Dodo Adamou Balkissou (DA)

Faculty of Medicine of Garoua, The University of Ngaoundere, Garoua, Cameroon.

Virginie Poka-Mayap (V)

Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.
Pulmonology Department, Yaoundé Jamot Hospital, Yaoundé, Cameroon.

Steve Voufouo Sonwa (SV)

Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.

Godwin Y Tatah (GY)

Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.
Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon.
Brain Research Africa Initiative (BRAIN), Geneva, Switzerland.
Neurology Department, Yaoundé Central Hospital, Yaoundé, Cameroon.

Leonard N Nfor (LN)

Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon.
Brain Research Africa Initiative (BRAIN), Geneva, Switzerland.
Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.

Michel K Mengnjo (MK)

Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon.
Brain Research Africa Initiative (BRAIN), Geneva, Switzerland.
Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.

Eric-Samuel Chokoke (ES)

Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon.
Brain Research Africa Initiative (BRAIN), Geneva, Switzerland.
Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.

Ben Patrick Michel Moutlen (BPM)

Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.

Stephen Perrig (S)

Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon.
Brain Research Africa Initiative (BRAIN), Geneva, Switzerland.
Sleep Studies Laboratory, Geneva University Hospitals, Geneva, Switzerland.

Eric Walter Pefura-Yone (EW)

Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.
Pulmonology Department, Yaoundé Jamot Hospital, Yaoundé, Cameroon.

Alfred Kongnyu Njamnshi (AK)

Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.
Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon.
Brain Research Africa Initiative (BRAIN), Geneva, Switzerland.
Neurology Department, Yaoundé Central Hospital, Yaoundé, Cameroon.

Classifications MeSH