Gli Phosphorylation Code in Hedgehog Signal Transduction.
CK1
Ci
Fu
GSK3
Gli
Hedgehog
PKA
Ulk3
Journal
Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250
Informations de publication
Date de publication:
2022
2022
Historique:
received:
31
12
2021
accepted:
04
01
2022
entrez:
21
2
2022
pubmed:
22
2
2022
medline:
22
2
2022
Statut:
epublish
Résumé
Hedgehog (Hh) family of secreted proteins governs many key processes in embryonic development and adult tissue homeostasis in species ranging from insects to human. Deregulation of Hh signaling has been implicated in a wide range of human diseases including birth defect and cancer. Hh signaling pathway culminates in the conversion of the latent transcription factor Cubitus interruptus (Ci)/Gli from a repressor form (Ci
Identifiants
pubmed: 35186941
doi: 10.3389/fcell.2022.846927
pii: 846927
pmc: PMC8855225
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
846927Subventions
Organisme : NIGMS NIH HHS
ID : R35 GM118063
Pays : United States
Informations de copyright
Copyright © 2022 Zhou and Jiang.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):12066-12071
pubmed: 31142652
J Cell Sci. 2010 Jan 1;123(Pt 1):62-9
pubmed: 20016067
Cell. 2021 May 27;184(11):2911-2926.e18
pubmed: 33932338
Clin Genet. 2005 Mar;67(3):193-208
pubmed: 15691355
J Cell Sci. 2019 Jan 22;132(2):
pubmed: 30578313
Semin Cancer Biol. 2021 Apr 6;:
pubmed: 33836254
Sci Signal. 2014 Jul 01;7(332):ra62
pubmed: 24985345
Development. 2015 Mar 1;142(5):931-42
pubmed: 25633354
Genes Dev. 1999 Nov 1;13(21):2828-37
pubmed: 10557210
Dev Cell. 2007 Oct;13(4):481-95
pubmed: 17925225
Development. 2011 Nov;138(22):4921-30
pubmed: 22007132
Nature. 1997 Apr 17;386(6626):735-8
pubmed: 9109493
Dev Cell. 2019 Sep 9;50(5):610-626.e4
pubmed: 31279575
Development. 1999 Oct;126(19):4331-9
pubmed: 10477300
J Biol Chem. 2010 Nov 26;285(48):37218-26
pubmed: 20876583
Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13069-13074
pubmed: 27799542
Cell. 2013 Jan 17;152(1-2):210-23
pubmed: 23332756
Mol Cell Biol. 2005 Aug;25(16):7054-68
pubmed: 16055717
Development. 2000 Oct;127(19):4293-301
pubmed: 10976059
Development. 2011 Jun;138(12):2533-42
pubmed: 21610030
Curr Biol. 2009 Aug 11;19(15):1320-6
pubmed: 19592253
J Cell Biol. 2010 Oct 18;191(2):415-28
pubmed: 20956384
Cell. 2002 Mar 22;108(6):823-35
pubmed: 11955435
Development. 2014 Sep;141(18):3445-57
pubmed: 25183867
Genes Dev. 2009 Aug 15;23(16):1910-28
pubmed: 19684112
J Biol Chem. 2006 Jul 14;281(28):19320-6
pubmed: 16651270
Nature. 2008 Dec 18;456(7224):967-70
pubmed: 18987629
Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13377-82
pubmed: 19666503
J Cell Biol. 1999 May 3;145(3):481-90
pubmed: 10225950
Mol Cell Biol. 2010 Apr;30(8):1910-22
pubmed: 20154143
Elife. 2020 Oct 21;9:
pubmed: 33084577
J Biol Chem. 2011 Apr 15;286(15):13502-11
pubmed: 21317289
Dev Cell. 2005 Dec;9(6):819-30
pubmed: 16326393
Cell. 2000 Feb 18;100(4):423-34
pubmed: 10693759
J Cell Biol. 2016 Mar 28;212(7):861-75
pubmed: 27002170
Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):E5651-60
pubmed: 25512501
Cell Res. 2011 Oct;21(10):1436-51
pubmed: 21844892
Development. 2011 Oct;138(19):4219-31
pubmed: 21852395
PLoS Biol. 2021 Apr 22;19(4):e3001191
pubmed: 33886552
Cell. 1997 Jul 25;90(2):235-45
pubmed: 9244298
J Biol Chem. 2015 Dec 4;290(49):29663-75
pubmed: 26451044
Proc Natl Acad Sci U S A. 2006 Jan 3;103(1):33-8
pubmed: 16371461
J Biol Chem. 2007 Apr 13;282(15):10846-52
pubmed: 17283082
Mol Cell Biol. 2006 Jun;26(11):4316-26
pubmed: 16705181
Mol Cell Biol. 2006 May;26(9):3365-77
pubmed: 16611981
Mol Cell Biol. 2005 Aug;25(16):7042-53
pubmed: 16055716
Annu Rev Cell Dev Biol. 2011;27:513-37
pubmed: 21801010
Cell. 1995 Feb 24;80(4):553-62
pubmed: 7867063
Development. 2010 Jul;137(13):2079-94
pubmed: 20530542
Nature. 2013 Feb 28;494(7438):484-8
pubmed: 23446420
Sci Signal. 2018 Sep 11;11(547):
pubmed: 30206138
Cell. 1995 Feb 24;80(4):563-72
pubmed: 7867064
PLoS Biol. 2017 Aug 4;15(8):e2002063
pubmed: 28777795
J Cell Sci. 2014 Mar 1;127(Pt 5):1092-103
pubmed: 24413177
Dev Cell. 2011 Jun 14;20(6):802-14
pubmed: 21664578
Trends Biochem Sci. 2020 May;45(5):397-410
pubmed: 32311334
Nature. 2007 Nov 8;450(7167):252-8
pubmed: 17960137
Nature. 2002 Apr 4;416(6880):548-52
pubmed: 11912487
Nature. 2019 Jul;571(7764):279-283
pubmed: 31168089
Genes Dev. 2010 Apr 1;24(7):670-82
pubmed: 20360384
Front Genet. 2019 Jun 12;10:556
pubmed: 31244888
Dev Cell. 2005 Feb;8(2):267-78
pubmed: 15691767
Genes Dev. 2003 Nov 1;17(21):2709-20
pubmed: 14597665
Nat Commun. 2014 Oct 07;5:5034
pubmed: 25289679
Dev Biol. 2017 Sep 1;429(1):147-157
pubmed: 28673820
Cell Res. 2013 Feb;23(2):186-200
pubmed: 23337587
Development. 2010 Jun;137(12):2001-9
pubmed: 20463034
Biochem Biophys Res Commun. 2009 Sep 25;387(3):569-74
pubmed: 19622347
Sci Signal. 2009 Jun 23;2(76):ra29
pubmed: 19549984
Cell Rep. 2014 Jan 16;6(1):168-181
pubmed: 24373970
Cell. 1999 Aug 6;98(3):305-16
pubmed: 10458606
J Cell Biol. 2013 Nov 25;203(4):575-83
pubmed: 24385484
J Biol Chem. 2018 Aug 31;293(35):13496-13508
pubmed: 30018136
Development. 2007 Oct;134(20):3677-89
pubmed: 17881487
Cancer Cell. 2012 Mar 20;21(3):374-87
pubmed: 22439934
Dev Cell. 2008 Dec;15(6):801-12
pubmed: 19081070
Exp Cell Res. 2010 Feb 15;316(4):627-37
pubmed: 19878745
Proc Natl Acad Sci U S A. 2015 May 19;112(20):6383-8
pubmed: 25941387
Int J Mol Sci. 2021 Dec 11;22(24):
pubmed: 34948134
Mol Cell. 2003 Nov;12(5):1261-74
pubmed: 14636583
Dev Cell. 2015 Nov 23;35(4):497-512
pubmed: 26585297
Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12607-12
pubmed: 16885213
Nature. 1998 Jan 29;391(6666):493-6
pubmed: 9461217
Cell. 1997 Jun 27;89(7):1043-53
pubmed: 9215627
Cold Spring Harb Perspect Biol. 2017 May 1;9(5):
pubmed: 27881449
Nature. 1998 Dec 24-31;396(6713):749-53
pubmed: 9874371
Cell. 1999 Mar 19;96(6):819-31
pubmed: 10102270