Peptide probes for proteases - innovations and applications for monitoring proteolytic activity.

Biomarkers Peptide Hydrolases / metabolism Peptides / metabolism Proteolysis

Journal

Chemical Society reviews
ISSN: 1460-4744
Titre abrégé: Chem Soc Rev
Pays: England
ID NLM: 0335405

Informations de publication

Date de publication:
21 Mar 2022
Historique:
pubmed: 22 2 2022
medline: 24 3 2022
entrez: 21 2 2022
Statut: epublish

Résumé

Proteases are excellent biomarkers for a variety of diseases, offer multiple opportunities for diagnostic applications and are valuable targets for therapy. From a chemistry-based perspective this review discusses and critiques the most recent advances in the field of substrate-based probes for the detection and analysis of proteolytic activity both

Identifiants

DOI: 10.1039/d1cs00798j PMID: 35188510
pubmed: 35188510
doi: 10.1039/d1cs00798j
doi:

Substances chimiques

Biomarkers 0
Peptides 0
Peptide Hydrolases EC 3.4.-

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

2081-2120

Auteurs

Maria Rodriguez-Rios (M)

EaStCHEM School of Chemistry, University of Edinburgh, David Brewster Road, EH9 3FJ Edinburgh, UK. Mark.Bradley@ed.ac.uk.
ORCID: 0000-0003-2434-1603

Alicia Megia-Fernandez (A)

EaStCHEM School of Chemistry, University of Edinburgh, David Brewster Road, EH9 3FJ Edinburgh, UK. Mark.Bradley@ed.ac.uk.
ORCID: 0000-0002-1373-8675

Daniel J Norman (DJ)

Technical University of Munich, Trogerstrasse, 30, 81675, Munich, Germany.
ORCID: 0000-0002-0056-061X

Mark Bradley (M)

EaStCHEM School of Chemistry, University of Edinburgh, David Brewster Road, EH9 3FJ Edinburgh, UK. Mark.Bradley@ed.ac.uk.
ORCID: 0000-0001-7893-1575

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Peptide probes for proteases - innovations and...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Peptide hydrolases › Peptide probes for proteases - innovations and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Peptide probes for proteases - innovations and...
questionsmedicales.fr › Métabolisme › Protéolyse › Peptide probes for proteases - innovations and...