Association between host genetics of sheep and the rumen microbial composition.


Journal

Tropical animal health and production
ISSN: 1573-7438
Titre abrégé: Trop Anim Health Prod
Pays: United States
ID NLM: 1277355

Informations de publication

Date de publication:
22 Feb 2022
Historique:
received: 30 01 2021
accepted: 04 01 2022
entrez: 22 2 2022
pubmed: 23 2 2022
medline: 25 2 2022
Statut: epublish

Résumé

A synergy between the rumen microbiota and the host genetics has created a symbiotic relationship, beneficial to the host's health. In this study, the association between the host genetics and rumen microbiome of Damara and Meatmaster sheep was investigated. The composition of rumen microbiota was estimated through the analysis of the V3-V4 region of the 16S rRNA gene, while the sheep blood DNA was genotyped with Illumina OvineSNP50 BeadChip and the genome-wide association (GWA) was analyzed. Sixty significant SNPs dispersed in 21 regions across the Ovis aries genome were found to be associated with the relative abundance of seven genera: Acinetobacter, Bacillus, Clostridium, Flavobacterium, Prevotella, Pseudomonas, and Streptobacillus. A total of eighty-four candidate genes were identified, and their functional annotations were mainly associated with immunity responses and function, metabolism, and signal transduction. Our results propose that those candidate genes identified in the study may be modulating the composition of rumen microbiota and further indicating the significance of comprehending the interactions between the host and rumen microbiota to gain better insight into the health of sheep.

Identifiants

pubmed: 35192073
doi: 10.1007/s11250-022-03057-2
pii: 10.1007/s11250-022-03057-2
doi:

Substances chimiques

RNA, Ribosomal, 16S 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

109

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer Nature B.V.

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Auteurs

Sinalo Mani (S)

GI Microbiology and Biotechnology Unit, Agricultural Research Council- Animal Production, Private Bag X02, Irene, 0062, South Africa.
Discipline of Genetics, School of Life Sciences, College of Agriculture, Engineering and Science, University of KwaZulu-Natal, Westville, P/Bag X54001, Durban, 4000, South Africa.

Olayinka Ayobami Aiyegoro (OA)

GI Microbiology and Biotechnology Unit, Agricultural Research Council- Animal Production, Private Bag X02, Irene, 0062, South Africa. ayoyinkaaiyegoro@gmail.com.
Research Unit for Environmental Sciences and Management, North West University, Potchefstroom, 2520, South Africa. ayoyinkaaiyegoro@gmail.com.

Matthew Adekunle Adeleke (MA)

Discipline of Genetics, School of Life Sciences, College of Agriculture, Engineering and Science, University of KwaZulu-Natal, Westville, P/Bag X54001, Durban, 4000, South Africa.

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