Evaluation of respiratory anatomical-functional sequelae in patients who recovered from COVID-19.

COVID-19 SARS-CoV-2 computerized tomography scan coronavirus pulmonary sequelae

Journal

Journal of infection in developing countries
ISSN: 1972-2680
Titre abrégé: J Infect Dev Ctries
Pays: Italy
ID NLM: 101305410

Informations de publication

Date de publication:
31 01 2022
Historique:
received: 27 08 2020
accepted: 25 08 2021
entrez: 22 2 2022
pubmed: 23 2 2022
medline: 26 2 2022
Statut: epublish

Résumé

Coronavirus disease 19 (COVID-19) has been a global public health emergency, with 209.89 million cases of infection with SARS-CoV-2 recorded, resulting in 4,401,675 deaths. After recuperation, it is probable that COVID-19 patients have sequelae of the disease. This study aimed to evaluate the respiratory anatomical-functional sequelae in Mexican patients who recovered from COVID-19. This study included twenty-four patients who recovered from COVID-19 and eight non-infected patients (controls). Participants were screened for SARS-CoV-2 and the presence of IgM/IgG antibodies. Pulmonary function and lung anatomical abnormalities were evaluated by spirometry and computerized tomography. A total of 45.8% of the patients had pulmonary function with obstructive patterns: 70.8% of recovered cases had COVID-19 Reporting and Data System (CO-RADS) 1, 20.8% CO-RADS 3 and 16.7% CO-RADS 4. A total of 35.3% of patients with CO-RADS 1 also showed bilateral nodal growth; 70.8% of patients tested positive for IgG and 8.4% for IgG/IgM, and 20.8% tested negative for both antibodies. There were respiratory anatomical and functional sequelae in Mexican patients who recovered from COVID-19, with a high occurrence of pulmonary obstructive patterns in the study population. These observations indicate the importance of the routine evaluation of sequelae in Mexican patients who recovered from COVID-19 and the need for strict follow-up to improve the quality of life of these patients.

Identifiants

pubmed: 35192524
doi: 10.3855/jidc.13772
doi:

Substances chimiques

Antibodies, Viral 0
Immunoglobulin M 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

73-80

Informations de copyright

Copyright (c) 2022 Margarita de la Luz Martinez-Fierro, Jose Isaias Badillo-Almaraz, Jose Ramon Munoz-Torres, Griselda Aide Cabral Pacheco, Idalia Garza-Veloz, Edgar Fernando Gutierrez-Vela, Lucia Socorro Hernandez-Marquez, Lizbeth Areli Hernandez-Marquez, Alondra Daniela Torres-Gaytan, Juan Carlos Alvarez-Castro, Claudia Caldera-Villalobos, Ivan Delgado-Enciso, Iram Pablo Rodriguez-Sanchez, Oscar Gustavo Meza-Zavala, Yolanda Ortiz-Castro.

Déclaration de conflit d'intérêts

No Conflict of Interest is declared

Auteurs

Margarita de la Luz Martinez-Fierro (ML)

Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, Mexico. margaritamf@uaz.edu.mx.

Jose Isaias Badillo-Almaraz (JI)

Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, Mexico.

Jose Ramon Muñoz-Torres (JR)

Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, Mexico.

Griselda Aide Cabral Pacheco (GA)

Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, Mexico.

Idalia Garza-Veloz (I)

Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, Mexico.

Edgar Fernando Gutierrez-Vela (EF)

General Hospital of Zacatecas "Luz González Cosío", Zacatecas Health Services, Zacatecas, México.

Lucia Socorro Hernandez-Marquez (LS)

Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, Mexico.

Lizbeth Areli Hernandez-Marquez (LA)

Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, Mexico.

Alondra Daniela Torres-Gaytan (AD)

Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, Mexico.

Juan Carlos Alvarez-Castro (JC)

Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, Mexico.

Claudia Caldera-Villalobos (C)

Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, Mexico.

Ivan Delgado-Enciso (I)

Department of Molecular Medicine, School of Medicine, University of Colima, Colima, Mexico.

Iram Pablo Rodriguez-Sanchez (IP)

Molecular and Structural Physiology Laboratory, School of Biological Sciences, Autonomous University of Nuevo León, Monterrey, Nuevo León, Mexico.

Oscar Gustavo Meza-Zavala (OG)

Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, Mexico.

Yolanda Ortiz-Castro (Y)

Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, Mexico.

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