Affimer Tagged Cubosomes: Targeting of Carcinoembryonic Antigen Expressing Colorectal Cancer Cells Using
Animals
Carcinoembryonic Antigen
/ metabolism
Carrier Proteins
/ metabolism
Cell Line
Click Chemistry
Colorectal Neoplasms
/ drug therapy
Drug Delivery Systems
Drug Liberation
Humans
Hydroxybutyrates
/ pharmacology
Liquid Crystals
/ chemistry
Mice, Inbred BALB C
Mice, Nude
Nanoparticles
/ chemistry
Pentanones
/ pharmacology
Xenograft Model Antitumor Assays
Affimers
active targeting
cancer
cubosomes
lipids
lyotropic liquid crystalline nanoparticles
Journal
ACS applied materials & interfaces
ISSN: 1944-8252
Titre abrégé: ACS Appl Mater Interfaces
Pays: United States
ID NLM: 101504991
Informations de publication
Date de publication:
09 Mar 2022
09 Mar 2022
Historique:
pubmed:
24
2
2022
medline:
31
3
2022
entrez:
23
2
2022
Statut:
ppublish
Résumé
Nanomedicines, while having been approved for cancer therapy, present many challenges such as low stability, rapid clearance, and nonspecificity leading to off-target toxicity. Cubosomes are porous lyotropic liquid crystalline nanoparticles that have shown great premise as drug delivery vehicles; however, their behavior
Identifiants
pubmed: 35196008
doi: 10.1021/acsami.1c21655
pmc: PMC9007418
doi:
Substances chimiques
Carcinoembryonic Antigen
0
Carrier Proteins
0
Hydroxybutyrates
0
Pentanones
0
acetyl acetonate
17272-66-1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
11078-11091Subventions
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/P001483/1
Pays : United Kingdom
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