Multiple Extrapulmonary Tuberculous Abscesses Developed Postpartum in a Non-HIV Patient Under Anti-tuberculosis Chemotherapy.

abscess extrapulmonary tuberculosis immune reconstitution lymhadenopathy paradoxical reaction post-partum

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
Jan 2022
Historique:
accepted: 16 01 2022
entrez: 24 2 2022
pubmed: 25 2 2022
medline: 25 2 2022
Statut: epublish

Résumé

Although abscess formation constitutes a recognized complication of tuberculous lymphadenitis, the concomitant development of multiple tuberculous abscesses in the course of tuberculous lymphadenitis has rarely been described in the literature among HIV-negative patients under appropriate chemotherapy. Adherence and sensitivity to the administered anti-tuberculosis chemotherapy have to be verified in such patients. We report a case of deteriorating tuberculous lymphadenitis, presenting with the development of multiple extrapulmonary abscesses (cervical, psoas, and retroperitoneal) in an HIV-negative patient who had complied with appropriate anti-tuberculosis chemotherapy for four months. Mycobacterium tuberculosis was the identified pathogen in specimens from the abscesses. Continuation of anti-tuberculosis medications and concurrent administration of antibiotics, along with CT-guided percutaneous drainage of the psoas abscess, resulted in gradual resolution of the patient's lesions. Interestingly, our patient had recent childbirth, indicating a potential association between the immunomodulatory processes during the postpartum period and the development of the so-called paradoxical reaction. Awareness of such complications should be raised, as a timely recognition and subsequent therapeutical treatment are essential for a favorable outcome.

Identifiants

pubmed: 35198302
doi: 10.7759/cureus.21395
pmc: PMC8855021
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e21395

Informations de copyright

Copyright © 2022, Papadopoulou et al.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Efthymia Papadopoulou (E)

Department of Pulmonary Medicine, George Papanikolaou General Hospital, Thessaloniki, GRC.

Christina Rampiadou (C)

Department of Pulmonary Medicine, George Papanikolaou General Hospital, Thessaloniki, GRC.

Evangelos Petsatodis (E)

Department of Interventional Radiology, George Papanikolaou General Hospital, Thessaloniki, GRC.

Diamantis Chloros (D)

Department of Pulmonary Medicine, George Papanikolaou General Hospital, Thessaloniki, GRC.

Afroditi Boutou (A)

Department of Pulmonary Medicine, George Papanikolaou General Hospital, Thessaloniki, GRC.

Classifications MeSH