Composite Clonal Analysis Reveals Transition of NSCLC Subtypes Through Accumulation of Gene Mutations: A Case Report.
Case report
Clonal analysis
EGFR
Gene mutations
NSCLC
Pathologic subtypes
Journal
JTO clinical and research reports
ISSN: 2666-3643
Titre abrégé: JTO Clin Res Rep
Pays: United States
ID NLM: 101769967
Informations de publication
Date de publication:
Feb 2022
Feb 2022
Historique:
received:
31
10
2021
revised:
22
12
2021
accepted:
05
01
2022
entrez:
24
2
2022
pubmed:
25
2
2022
medline:
25
2
2022
Statut:
epublish
Résumé
We analyzed an EGFR-mutated lung cancer with a pathologic diagnosis of combined large cell neuroendocrine carcinoma with mixed adenocarcinoma subtypes. Targeted next-generation sequencing of each component suggested that mutations in
Identifiants
pubmed: 35199052
doi: 10.1016/j.jtocrr.2022.100277
pii: S2666-3643(22)00002-9
pmc: PMC8844245
doi:
Types de publication
Case Reports
Langues
eng
Pagination
100277Informations de copyright
© 2022 The Authors.
Références
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pubmed: 24457237
J Clin Oncol. 2017 Sep 10;35(26):3065-3074
pubmed: 28498782
Lancet Oncol. 2015 Apr;16(4):e165-72
pubmed: 25846096