Chiral-Phosphoric-Acid-Catalyzed C6-Selective Pictet-Spengler Reactions for Construction of Polycyclic Indoles Containing Spiro Quaternary Stereocenters.
Journal
Organic letters
ISSN: 1523-7052
Titre abrégé: Org Lett
Pays: United States
ID NLM: 100890393
Informations de publication
Date de publication:
04 Mar 2022
04 Mar 2022
Historique:
pubmed:
25
2
2022
medline:
25
2
2022
entrez:
24
2
2022
Statut:
ppublish
Résumé
Compared with the well-established asymmetric Pictet-Spengler reactions on the pyrrole ring of indoles, the catalytic asymmetric Pictet-Spengler reaction on the benzene ring of indoles has been rarely studied. Herein the C6-selective Pictet-Spengler reactions of indoles have been realized by employing 2-(1
Identifiants
pubmed: 35199528
doi: 10.1021/acs.orglett.2c00368
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM