Reducing the Pill Burden: Immunosuppressant Adherence and Safety after Conversion from a Twice-Daily (IR-Tac) to a Novel Once-Daily (LCP-Tac) Tacrolimus Formulation in 161 Liver Transplant Patients.
immunosuppressant adherence
immunosuppressant efficacy
liver transplantation
tacrolimus
Journal
Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304
Informations de publication
Date de publication:
26 Jan 2022
26 Jan 2022
Historique:
received:
24
11
2021
revised:
02
01
2022
accepted:
03
01
2022
entrez:
25
2
2022
pubmed:
26
2
2022
medline:
26
2
2022
Statut:
epublish
Résumé
Non-adherence to immunosuppressant therapy reduces long-term graft and patient survival after solid organ transplantation. The objective of this 24-month prospective study was to determine adherence, efficacy and safety after conversion of stable liver transplant (LT) recipients from a standard twice-daily immediate release Tacrolimus (IR-Tac) to a novel once-daily life cycle pharma Tacrolimus (LCP-Tac) formulation. We converted a total of 161 LT patients at baseline, collecting Tacrolimus trough levels, laboratories, physical examination data and the BAASIS
Identifiants
pubmed: 35203481
pii: biomedicines10020272
doi: 10.3390/biomedicines10020272
pmc: PMC8869578
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Chiesi GmbH
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