Point Prevalence Survey of Antibiotic Use across 13 Hospitals in Uganda.
Uganda
antibiotic use surveillance
antimicrobial stewardship
antimicrobials
global health security
hospital
point prevalence survey
private sector
Journal
Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404
Informations de publication
Date de publication:
04 Feb 2022
04 Feb 2022
Historique:
received:
21
12
2021
revised:
19
01
2022
accepted:
27
01
2022
entrez:
25
2
2022
pubmed:
26
2
2022
medline:
26
2
2022
Statut:
epublish
Résumé
Standardized monitoring of antibiotic use underpins the effective implementation of antimicrobial stewardship interventions in combatting antimicrobial resistance (AMR). To date, few studies have assessed antibiotic use in hospitals in Uganda to identify gaps that require intervention. This study applied the World Health Organization's standardized point prevalence survey methodology to assess antibiotic use in 13 public and private not-for-profit hospitals across the country. Data for 1077 patients and 1387 prescriptions were collected between December 2020 and April 2021 and analyzed to understand the characteristics of antibiotic use and the prevalence of the types of antibiotics to assess compliance with Uganda Clinical Guidelines; and classify antibiotics according to the WHO Access, Watch, and Reserve classification. This study found that 74% of patients were on one or more antibiotics. Compliance with Uganda Clinical Guidelines was low (30%); Watch-classified antibiotics were used to a high degree (44% of prescriptions), mainly driven by the wide use of ceftriaxone, which was the most frequently used antibiotic (37% of prescriptions). The results of this study identify key areas for the improvement of antimicrobial stewardship in Uganda and are important benchmarks for future evaluations.
Identifiants
pubmed: 35203802
pii: antibiotics11020199
doi: 10.3390/antibiotics11020199
pmc: PMC8868487
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : United States Agency for International Development
ID : 7200AA18C00074
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