The Shape of the Olfactory Bulb Predicts Olfactory Function.
MRI
anosmia
deformation
olfaction
olfactory bulb shape
plasticity
smell
Journal
Brain sciences
ISSN: 2076-3425
Titre abrégé: Brain Sci
Pays: Switzerland
ID NLM: 101598646
Informations de publication
Date de publication:
18 Jan 2022
18 Jan 2022
Historique:
received:
24
11
2021
revised:
13
01
2022
accepted:
14
01
2022
entrez:
25
2
2022
pubmed:
26
2
2022
medline:
26
2
2022
Statut:
epublish
Résumé
The olfactory bulb (OB) plays a key role in the processing of olfactory information. A large body of research has shown that OB volumes correlate with olfactory function, which provides diagnostic and prognostic information in olfactory dysfunction. Still, the potential value of the OB shape remains unclear. Based on our clinical experience we hypothesized that the shape of the OB predicts olfactory function, and that it is linked to olfactory loss, age, and gender. The aim of this study was to produce a classification of OB shape in the human brain, scalable to clinical and research applications. Results from patients with the five most frequent causes of olfactory dysfunction (
Identifiants
pubmed: 35203892
pii: brainsci12020128
doi: 10.3390/brainsci12020128
pmc: PMC8870545
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : TU Dresden
ID : n
Références
J Neurol. 2017 Apr;264(4):631-638
pubmed: 27393116
JAMA Otolaryngol Head Neck Surg. 2019 Sep 1;145(9):846-853
pubmed: 31318413
Anat Rec. 1987 May;218(1):73-87
pubmed: 3605663
Neuropathol Appl Neurobiol. 2003 Jun;29(3):303-11
pubmed: 12787327
Nature. 1992 Nov 26;360(6402):339-40
pubmed: 1448149
Brain Imaging Behav. 2017 Aug;11(4):998-1005
pubmed: 27448159
Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15613-8
pubmed: 20679234
Nat Rev Neurosci. 2009 Aug;10(8):611-8
pubmed: 19584894
Sci Am. 1995 Oct;273(4):154-9
pubmed: 7481719
Brain. 2009 Nov;132(Pt 11):3096-101
pubmed: 19773353
Chem Senses. 1997 Feb;22(1):39-52
pubmed: 9056084
Neuroimage. 2012 Apr 15;60(3):1662-70
pubmed: 22306806
PLoS One. 2008 Jul 09;3(7):e2640
pubmed: 18612420
Science. 2007 Mar 2;315(5816):1243-9
pubmed: 17303719
Ophthalmic Physiol Opt. 2012 May;32(3):184-99
pubmed: 22486366
Acad Radiol. 1999 May;6(5):264-72
pubmed: 10228615
J Craniofac Surg. 2014 Mar;25(2):359-62
pubmed: 24561363
Ann N Y Acad Sci. 1998 Nov 30;855:708-15
pubmed: 9929675
Cell. 1996 Nov 15;87(4):675-86
pubmed: 8929536
J Neurol. 2015;262(4):1046-51
pubmed: 25712545
Rhinology. 2016 Jan 31;56(1):1-30
pubmed: 28623665
Neuroscience. 2013 May 1;237:51-5
pubmed: 23376116
Neuroimage. 2008 Aug 15;42(2):498-502
pubmed: 18555701
Acta Otolaryngol. 1971 Jan;71(1):49-62
pubmed: 5100075
J Comp Neurol. 2002 Dec 23;454(4):361-72
pubmed: 12455003
Brain. 2017 Oct 1;140(10):2722-2736
pubmed: 28969383
Arch Otorhinolaryngol. 1986;243(2):112-6
pubmed: 3718322
Curr Opin Neurobiol. 2020 Oct;64:17-23
pubmed: 32062045
Eur Arch Otorhinolaryngol. 2010 Oct;267(10):1551-6
pubmed: 20300763
Eur Arch Otorhinolaryngol. 2016 Jan;273(1):1-7
pubmed: 25308243
Nat Commun. 2016 Aug 31;7:12659
pubmed: 27578235
Chem Senses. 2019 Jul 17;44(6):357-364
pubmed: 31077277
AJNR Am J Neuroradiol. 2009 Jun;30(6):1149-52
pubmed: 19279285
Ann N Y Acad Sci. 1998 Nov 30;855:546-55
pubmed: 9929650
Philos Trans R Soc Lond B Biol Sci. 2020 Jun 8;375(1800):20190265
pubmed: 32306872
J Anat. 2016 Feb;228(2):324-37
pubmed: 25911945
Brain Imaging Behav. 2018 Oct;12(5):1355-1362
pubmed: 29234959
Molecules. 2013 Sep 17;18(9):11586-600
pubmed: 24048289
Laryngoscope. 2006 Jun;116(6):901-5
pubmed: 16735894
Parkinsons Dis. 2011;2011:450939
pubmed: 21687752