Detection of Splenic Tissue Using
RBC
accessory spleen
peritoneal carcinomatosis
selective spleen scintigraphy
splenosis
splenule
Journal
Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402
Informations de publication
Date de publication:
14 Feb 2022
14 Feb 2022
Historique:
received:
01
02
2022
revised:
11
02
2022
accepted:
12
02
2022
entrez:
25
2
2022
pubmed:
26
2
2022
medline:
26
2
2022
Statut:
epublish
Résumé
Red blood cells (RBC) scintigraphy can be used not only for detection of bleeding sites, but also of spleen tissue. However, there is no established quantitative readout. Therefore, we investigated uptake in suspected splenic lesions in direct quantitative correlation to sites of physiologic uptake in order to objectify the readout. 20 patients with Tc-99m-labelled RBC scintigraphy and SPECT/low-dose CT for assessment of suspected splenic tissue were included. Lesions were rated as vital splenic or non-splenic tissue, and uptake and physiologic uptake of bone marrow, pancreas, and spleen were then quantified using a volume-of-interest based approach. Hepatic uptake served as a reference. The median uptake ratio was significantly higher in splenic (2.82 (range, 0.58-24.10), As the uptake in extra-splenic regions is invariably low compared to splenules, it can be used as comparator for evaluating suspected splenic tissues.
Sections du résumé
BACKGROUND
BACKGROUND
Red blood cells (RBC) scintigraphy can be used not only for detection of bleeding sites, but also of spleen tissue. However, there is no established quantitative readout. Therefore, we investigated uptake in suspected splenic lesions in direct quantitative correlation to sites of physiologic uptake in order to objectify the readout.
METHODS
METHODS
20 patients with Tc-99m-labelled RBC scintigraphy and SPECT/low-dose CT for assessment of suspected splenic tissue were included. Lesions were rated as vital splenic or non-splenic tissue, and uptake and physiologic uptake of bone marrow, pancreas, and spleen were then quantified using a volume-of-interest based approach. Hepatic uptake served as a reference.
RESULTS
RESULTS
The median uptake ratio was significantly higher in splenic (2.82 (range, 0.58-24.10),
CONCLUSION
CONCLUSIONS
As the uptake in extra-splenic regions is invariably low compared to splenules, it can be used as comparator for evaluating suspected splenic tissues.
Identifiants
pubmed: 35204576
pii: diagnostics12020486
doi: 10.3390/diagnostics12020486
pmc: PMC8871479
pii:
doi:
Types de publication
Journal Article
Langues
eng
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