APR-246-The Mutant TP53 Reactivator-Increases the Effectiveness of Berberine and Modified Berberines to Inhibit the Proliferation of Pancreatic Cancer Cells.


Journal

Biomolecules
ISSN: 2218-273X
Titre abrégé: Biomolecules
Pays: Switzerland
ID NLM: 101596414

Informations de publication

Date de publication:
08 02 2022
Historique:
received: 11 01 2022
revised: 04 02 2022
accepted: 04 02 2022
entrez: 25 2 2022
pubmed: 26 2 2022
medline: 5 4 2022
Statut: epublish

Résumé

Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer. In ~75% of PDAC, the tumor suppressor

Identifiants

pubmed: 35204775
pii: biom12020276
doi: 10.3390/biom12020276
pmc: PMC8961609
pii:
doi:

Substances chimiques

Quinuclidines 0
TP53 protein, human 0
Tumor Suppressor Protein p53 0
Berberine 0I8Y3P32UF
eprenetapopt Z41TGB4080

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

James Andrew McCubrey (JA)

Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27858, USA.

Stephen L Abrams (SL)

Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27858, USA.

Linda S Steelman (LS)

Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27858, USA.

Lucio Cocco (L)

Department of Biomedical and Neuromotor Sciences, Università di Bologna, 40126 Bologna, Italy.

Stefano Ratti (S)

Department of Biomedical and Neuromotor Sciences, Università di Bologna, 40126 Bologna, Italy.

Alberto M Martelli (AM)

Department of Biomedical and Neuromotor Sciences, Università di Bologna, 40126 Bologna, Italy.

Paolo Lombardi (P)

Naxospharma, Via Giuseppe Di Vittorio 70, 20026 Novate Milanese, Italy.

Agnieszka Gizak (A)

Department of Molecular Physiology and Neurobiology, University of Wrocław, 50-335 Wroclaw, Poland.

Przemysław Duda (P)

Department of Molecular Physiology and Neurobiology, University of Wrocław, 50-335 Wroclaw, Poland.

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