Evolution of SARS-CoV-2 IgG Seroprevalence in Children and Factors Associated with Seroconversion: Results from a Multiple Time-Points Study in Friuli-Venezia Giulia Region, Italy.

COVID-19 IgG antibodies Italy children seroprevalence

Journal

Children (Basel, Switzerland)
ISSN: 2227-9067
Titre abrégé: Children (Basel)
Pays: Switzerland
ID NLM: 101648936

Informations de publication

Date de publication:
12 Feb 2022
Historique:
received: 17 12 2021
revised: 01 02 2022
accepted: 08 02 2022
entrez: 25 2 2022
pubmed: 26 2 2022
medline: 26 2 2022
Statut: epublish

Résumé

Data on the effective burden of the SARS-CoV-2 pandemic in the pediatric population are limited. We aimed at assessing the prevalence of SARS-CoV-2 IgG antibodies in children at three subsequent time-points. The study was conducted between January 2021 and July 2021 among children referring to the Research Institute for Maternal and Child Health "Burlo Garofolo" in Trieste, a referral regional hospital in Friuli Venezia Giulia, Italy. A multivariate analysis was conducted to assess factors independently associated with seroconversion. A total of 594 children were included. Anti-SARS-CoV-2 trimeric Spike protein IgG antibodies were found in 32 (15.4%) children tested in April-May and in 20 (11.8%) in June-July 2021, compared with 24 (11.1%) of those tested in January-February 2021 (

Identifiants

pubmed: 35204966
pii: children9020246
doi: 10.3390/children9020246
pmc: PMC8870333
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Marzia Lazzerini (M)

Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", 34137 Trieste, Italy.

Simone Benvenuto (S)

Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.

Ilaria Mariani (I)

Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", 34137 Trieste, Italy.

Giorgio Fedele (G)

Italian National Institute of Health, 00161 Rome, Italy.

Pasqualina Leone (P)

Italian National Institute of Health, 00161 Rome, Italy.

Paola Stefanelli (P)

Italian National Institute of Health, 00161 Rome, Italy.

Giada Vittori (G)

Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", 34137 Trieste, Italy.

Silvana Schreiber (S)

Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", 34137 Trieste, Italy.

Alberto Tommasini (A)

Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", 34137 Trieste, Italy.
Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.

Giovanni Rezza (G)

Italian National Institute of Health, 00161 Rome, Italy.

Egidio Barbi (E)

Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", 34137 Trieste, Italy.
Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.

Manola Comar (M)

Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", 34137 Trieste, Italy.
Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.

Classifications MeSH