Journal

Genes
ISSN: 2073-4425
Titre abrégé: Genes (Basel)
Pays: Switzerland
ID NLM: 101551097

Informations de publication

Date de publication:
28 01 2022
Historique:
received: 06 01 2022
revised: 21 01 2022
accepted: 24 01 2022
entrez: 25 2 2022
pubmed: 26 2 2022
medline: 22 4 2022
Statut: epublish

Résumé

Stochastic models of replication timing posit that origin firing timing is regulated by origin firing probability, with early-firing origins having a high probability of firing and late-firing origins having a lower probability. However, they offer no insight into why one origin should have a higher firing probability than another. Here, a simple framework is suggested for how to approach the question by noting that the firing probability (

Identifiants

pubmed: 35205293
pii: genes13020249
doi: 10.3390/genes13020249
pmc: PMC8872135
pii:
doi:

Substances chimiques

DNA Helicases EC 3.6.4.-

Types de publication

Journal Article Research Support, N.I.H., Extramural Review

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM125872
Pays : United States

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Auteurs

Nicholas Rhind (N)

Biochemistry and Molecular Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA.

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Classifications MeSH