Identification of Atypical Circulating Tumor Cells with Prognostic Value in Metastatic Breast Cancer Patients.

CTC CTM biomarker breast cancer circulating tumor cells cluster epithelial-to-mesenchymal transition metastases plasticity survival

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
13 Feb 2022
Historique:
received: 21 12 2021
revised: 03 02 2022
accepted: 09 02 2022
entrez: 25 2 2022
pubmed: 26 2 2022
medline: 26 2 2022
Statut: epublish

Résumé

Circulating tumor cells have a strong potential as a quasi-non-invasive tool for setting up a precision medicine strategy for cancer patients. Using a second-generation "filtration-based" technology to isolate CTCs, the Screencell™ technology (Sarcelles, France), we performed a large and simultaneous analysis of all atypical circulating tumor cells (

Identifiants

pubmed: 35205679
pii: cancers14040932
doi: 10.3390/cancers14040932
pmc: PMC8869799
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : La Ligue contre le cancer
ID : EL2016.LNCC/DaB; EL2019.LNCC/FB
Organisme : Association Ruban Rose
ID : Grand Prix (DB and FB)
Organisme : Foundation Groupe EDF
ID : EDF nanos
Organisme : Foundation ARC
ID : DOC20180507420
Organisme : Foundation ARC
ID : PDF20180507565
Organisme : Foundation de France
ID : 00107936
Organisme : Institut Paoli-Calmettes
ID : SIRIC INCa-DGOS-Inserm 6038

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Auteurs

Alexia Lopresti (A)

Laboratory of Predictive Oncology, Cancer Research Center of Marseille, Inserm U1068-CNRS UMR7258-Université Aix-Marseille UM105, Label "Ligue Contre le Cancer", 13009 Marseille, France.

Claire Acquaviva (C)

Laboratory of Predictive Oncology, Cancer Research Center of Marseille, Inserm U1068-CNRS UMR7258-Université Aix-Marseille UM105, Label "Ligue Contre le Cancer", 13009 Marseille, France.

Laurys Boudin (L)

Laboratory of Predictive Oncology, Cancer Research Center of Marseille, Inserm U1068-CNRS UMR7258-Université Aix-Marseille UM105, Label "Ligue Contre le Cancer", 13009 Marseille, France.

Pascal Finetti (P)

Laboratory of Predictive Oncology, Cancer Research Center of Marseille, Inserm U1068-CNRS UMR7258-Université Aix-Marseille UM105, Label "Ligue Contre le Cancer", 13009 Marseille, France.

Séverine Garnier (S)

Laboratory of Predictive Oncology, Cancer Research Center of Marseille, Inserm U1068-CNRS UMR7258-Université Aix-Marseille UM105, Label "Ligue Contre le Cancer", 13009 Marseille, France.

Anaïs Aulas (A)

Laboratory of Predictive Oncology, Cancer Research Center of Marseille, Inserm U1068-CNRS UMR7258-Université Aix-Marseille UM105, Label "Ligue Contre le Cancer", 13009 Marseille, France.

Maria Lucia Liberatoscioli (ML)

Laboratory of Predictive Oncology, Cancer Research Center of Marseille, Inserm U1068-CNRS UMR7258-Université Aix-Marseille UM105, Label "Ligue Contre le Cancer", 13009 Marseille, France.

Olivier Cabaud (O)

Laboratory of Predictive Oncology, Cancer Research Center of Marseille, Inserm U1068-CNRS UMR7258-Université Aix-Marseille UM105, Label "Ligue Contre le Cancer", 13009 Marseille, France.

Arnaud Guille (A)

Laboratory of Predictive Oncology, Cancer Research Center of Marseille, Inserm U1068-CNRS UMR7258-Université Aix-Marseille UM105, Label "Ligue Contre le Cancer", 13009 Marseille, France.

Alexandre de Nonneville (A)

Laboratory of Predictive Oncology, Cancer Research Center of Marseille, Inserm U1068-CNRS UMR7258-Université Aix-Marseille UM105, Label "Ligue Contre le Cancer", 13009 Marseille, France.

Quentin Da Costa (Q)

Laboratory of Predictive Oncology, Cancer Research Center of Marseille, Inserm U1068-CNRS UMR7258-Université Aix-Marseille UM105, Label "Ligue Contre le Cancer", 13009 Marseille, France.

Emilie Denicolai (E)

Laboratory of Predictive Oncology, Cancer Research Center of Marseille, Inserm U1068-CNRS UMR7258-Université Aix-Marseille UM105, Label "Ligue Contre le Cancer", 13009 Marseille, France.

Jihane Pakradouni (J)

Sponsor Unit, Department of Clinical Research and Innovation, Institut Paoli-Calmettes, 13009 Marseille, France.

Anthony Goncalves (A)

Department of Medical Oncology, Institut Paoli-Calmettes, 13009 Marseille, France.

Daniel Birnbaum (D)

Laboratory of Predictive Oncology, Cancer Research Center of Marseille, Inserm U1068-CNRS UMR7258-Université Aix-Marseille UM105, Label "Ligue Contre le Cancer", 13009 Marseille, France.

François Bertucci (F)

Laboratory of Predictive Oncology, Cancer Research Center of Marseille, Inserm U1068-CNRS UMR7258-Université Aix-Marseille UM105, Label "Ligue Contre le Cancer", 13009 Marseille, France.
Department of Medical Oncology, Institut Paoli-Calmettes, 13009 Marseille, France.

Emilie Mamessier (E)

Laboratory of Predictive Oncology, Cancer Research Center of Marseille, Inserm U1068-CNRS UMR7258-Université Aix-Marseille UM105, Label "Ligue Contre le Cancer", 13009 Marseille, France.

Classifications MeSH