Fungal Infections and Nail Psoriasis: An Update.
dermatophytes
nail psoriasis
non-dermatophyte molds
onychomycoses
yeasts
Journal
Journal of fungi (Basel, Switzerland)
ISSN: 2309-608X
Titre abrégé: J Fungi (Basel)
Pays: Switzerland
ID NLM: 101671827
Informations de publication
Date de publication:
03 Feb 2022
03 Feb 2022
Historique:
received:
05
01
2022
revised:
30
01
2022
accepted:
01
02
2022
entrez:
25
2
2022
pubmed:
26
2
2022
medline:
26
2
2022
Statut:
epublish
Résumé
The relationship between psoriasis and onychomycosis is controversial, and the exact nature of this association remains to be clearly elucidated. In healthy nails, the compact nail plate acts as a barrier, preventing any infection. In psoriatic nails, the nail plate involvement, together with abnormalities in the blood capillaries, may lead to decreased natural defenses against microorganisms. Moreover, onycholysis (detachment of the nail plate) induces a humid environment that may favor fungal proliferation. Treatment with immunosuppressive drugs may additionally enhance onychomycosis. In this comprehensive review, we present data regarding the incidence and pathogenic action of dermatophytes and other fungi in the development of fungal infection in psoriatic nails.
Identifiants
pubmed: 35205908
pii: jof8020154
doi: 10.3390/jof8020154
pmc: PMC8878282
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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