Normal Values and Patterns of Normality and Physiological Variability of Mitral and Tricuspid Inflow Pulsed Doppler in Healthy Children.

congenital diastolic function doppler echocardiography heart defects right ventricle ventricular dysfunction

Journal

Healthcare (Basel, Switzerland)
ISSN: 2227-9032
Titre abrégé: Healthcare (Basel)
Pays: Switzerland
ID NLM: 101666525

Informations de publication

Date de publication:
11 Feb 2022
Historique:
received: 27 12 2021
revised: 29 01 2022
accepted: 08 02 2022
entrez: 25 2 2022
pubmed: 26 2 2022
medline: 26 2 2022
Statut: epublish

Résumé

While mitral (MV) and tricuspid valve (TV) pulsed Doppler velocities and derived gradients are commonly evaluated, data on normal pediatric values are limited. This study aimed to evaluate the normal values and physiological variability for MV and TV Doppler velocities and derived gradients in a large cohort of prospectively enrolled healthy children. The echocardiographic measurements included pulsed Doppler MV and TV E and A velocities, E deceleration times (EDT), maximal and mean gradients, and velocity time integral (VTI). A total of 544 healthy subjects (median age 6.4 years, range 1 day-17.68 years) were included. MV and TV E velocity, E/A ratio, and E and A wave duration increased, while A velocity decreased with age ( We report normal values and patterns of normality and physiological variability for MV and TV inflow Doppler from a large population of healthy children.

Sections du résumé

BACKGROUND BACKGROUND
While mitral (MV) and tricuspid valve (TV) pulsed Doppler velocities and derived gradients are commonly evaluated, data on normal pediatric values are limited. This study aimed to evaluate the normal values and physiological variability for MV and TV Doppler velocities and derived gradients in a large cohort of prospectively enrolled healthy children.
METHODS METHODS
The echocardiographic measurements included pulsed Doppler MV and TV E and A velocities, E deceleration times (EDT), maximal and mean gradients, and velocity time integral (VTI).
RESULTS RESULTS
A total of 544 healthy subjects (median age 6.4 years, range 1 day-17.68 years) were included. MV and TV E velocity, E/A ratio, and E and A wave duration increased, while A velocity decreased with age (
CONCLUSIONS CONCLUSIONS
We report normal values and patterns of normality and physiological variability for MV and TV inflow Doppler from a large population of healthy children.

Identifiants

pubmed: 35206969
pii: healthcare10020355
doi: 10.3390/healthcare10020355
pmc: PMC8871925
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Italian Health Ministry Finalized Research Young Research Award
ID : GR-211-02350662

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Auteurs

Massimiliano Cantinotti (M)

Fondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.
Institute of Clinical Physiology, 56121 Pisa, Italy.

Pietro Marchese (P)

Fondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.

Marco Scalese (M)

Institute of Clinical Physiology, 56121 Pisa, Italy.

Eliana Franchi (E)

Fondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.

Nadia Assanta (N)

Fondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.

Martin Koestenberger (M)

Department of Pediatrics, Division of Pediatric Cardiology, Medical University, 8036 Graz, Austria.

Jef Van den Eynde (J)

Helen B. Taussig Heart Center, Johns Hopkins Hospital, Baltimore, MD 21218, USA.

Shelby Kutty (S)

Helen B. Taussig Heart Center, Johns Hopkins Hospital, Baltimore, MD 21218, USA.

Raffaele Giordano (R)

Adult and Pediatric Cardiac Surgery, Department of Advanced Biomedical Sciences, University of Naples "Federico II", 80138 Naples, Italy.

Classifications MeSH