Endothelial Ion Channels and Cell-Cell Communication in the Microcirculation.

arterioles blood flow capillaries endothelial cells endothelial ion channels and cell-cell communication ion channels functional hyperemia pericytes vascular smooth muscle cells

Journal

Frontiers in physiology
ISSN: 1664-042X
Titre abrégé: Front Physiol
Pays: Switzerland
ID NLM: 101549006

Informations de publication

Date de publication:
2022
Historique:
received: 29 10 2021
accepted: 05 01 2022
entrez: 25 2 2022
pubmed: 26 2 2022
medline: 26 2 2022
Statut: epublish

Résumé

Endothelial cells in resistance arteries, arterioles, and capillaries express a diverse array of ion channels that contribute to Cell-Cell communication in the microcirculation. Endothelial cells are tightly electrically coupled to their neighboring endothelial cells by gap junctions allowing ion channel-induced changes in membrane potential to be conducted for considerable distances along the endothelial cell tube that lines arterioles and forms capillaries. In addition, endothelial cells may be electrically coupled to overlying smooth muscle cells in arterioles and to pericytes in capillaries

Identifiants

pubmed: 35211031
doi: 10.3389/fphys.2022.805149
pmc: PMC8861442
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

805149

Informations de copyright

Copyright © 2022 Jackson.

Déclaration de conflit d'intérêts

The author declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

William F Jackson (WF)

Department of Pharmacology and Toxicology, College of Osteopathic Medicine, Michigan State University, East Lansing, MI, United States.

Classifications MeSH