Epstein-Barr Virus Infection in Lung Cancer: Insights and Perspectives.
Epstein–Barr virus
cancer
lung
Journal
Pathogens (Basel, Switzerland)
ISSN: 2076-0817
Titre abrégé: Pathogens
Pays: Switzerland
ID NLM: 101596317
Informations de publication
Date de publication:
21 Jan 2022
21 Jan 2022
Historique:
received:
15
12
2021
revised:
17
01
2022
accepted:
17
01
2022
entrez:
26
2
2022
pubmed:
27
2
2022
medline:
27
2
2022
Statut:
epublish
Résumé
Lung cancer (LC) is the leading cause of cancer death worldwide. Tobacco smoke is the most frequent risk factor etiologically associated with LC, although exposures to other environmental factors such as arsenic, radon or asbestos are also involved. Additionally, the involvement of some viral infections such as high-risk human papillomaviruses (HR-HPVs), Merkel cell polyomavirus (MCPyV), Jaagsiekte Sheep Retrovirus (JSRV), John Cunningham Virus (JCV), and Epstein-Barr virus (EBV) has been suggested in LC, though an etiological relationship has not yet been established. EBV is a ubiquitous gamma herpesvirus causing persistent infections and some lymphoid and epithelial tumors. Since EBV is heterogeneously detected in LCs from different parts of the world, in this review we address the epidemiological and experimental evidence of a potential role of EBV. Considering this evidence, we propose mechanisms potentially involved in EBV-associated lung carcinogenesis. Additional studies are warranted to dissect the role of EBV in this very frequent malignancy.
Identifiants
pubmed: 35215076
pii: pathogens11020132
doi: 10.3390/pathogens11020132
pmc: PMC8878590
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Int J Cancer. 2014 Feb 15;134(4):948-53
pubmed: 23904115
Mod Pathol. 2004 Feb;17(2):158-64
pubmed: 14752524
Int J Biol Sci. 2016 Oct 18;12(11):1309-1318
pubmed: 27877083
Cancer. 2017 Nov 1;123(21):4099-4105
pubmed: 28743157
Clin Cancer Res. 2002 Sep;8(9):2883-9
pubmed: 12231532
J Natl Cancer Inst. 1997 Sep 17;89(18):1366-73
pubmed: 9308707
Nature. 1985 Nov 7-13;318(6041):69-73
pubmed: 2997622
J Pathol. 1995 Nov;177(3):233-40
pubmed: 8551384
Chemosphere. 2003 Sep;52(9):1411-22
pubmed: 12867171
Oncotarget. 2017 Jan 3;8(1):268-284
pubmed: 27902485
Genes Dev. 2015 Jul 15;29(14):1447-62
pubmed: 26220992
Pharmacol Ther. 2015 Oct;154:67-77
pubmed: 26205191
Cancer Manag Res. 2018 Sep 10;10:3393-3404
pubmed: 30237741
Proc Natl Acad Sci U S A. 2019 Aug 6;116(32):16046-16055
pubmed: 31341086
Front Genet. 2016 May 11;7:85
pubmed: 27242894
Exp Mol Pathol. 2010 Dec;89(3):222-6
pubmed: 20699096
J Virol. 2008 Aug;82(16):8124-37
pubmed: 18524825
J Natl Cancer Inst. 2012 Sep 19;104(18):1396-410
pubmed: 22972969
Semin Cancer Biol. 2014 Jun;26:60-8
pubmed: 24457012
Clin Respir J. 2018 Feb;12(2):418-424
pubmed: 27421948
Am J Respir Crit Care Med. 2008 Feb 1;177(3):342-7
pubmed: 17989344
Pathol Oncol Res. 2021 Jun 18;27:1609775
pubmed: 34257619
Microorganisms. 2020 Nov 19;8(11):
pubmed: 33228078
J Virol. 2005 Jun;79(12):7641-7
pubmed: 15919916
Environ Int. 2020 Oct;143:105925
pubmed: 32623224
Viruses. 2021 May 11;13(5):
pubmed: 34064727
Oncology. 2015;89(3):125-36
pubmed: 25967534
J Clin Pathol. 2002 Dec;55(12):885-91
pubmed: 12461047
J Virol. 2009 Aug;83(15):7749-60
pubmed: 19439479
PLoS One. 2016 Apr 08;11(4):e0152737
pubmed: 27058955
Genes Cancer. 2011 Apr;2(4):466-74
pubmed: 21779514
Diagn Cytopathol. 2012 Sep;40(9):820-5
pubmed: 21433005
Eur J Pharmacol. 2005 Jul 11;517(3):246-51
pubmed: 15963492
Blood. 1994 Dec 1;84(11):3792-8
pubmed: 7949135
Science. 2004 Apr 30;304(5671):734-6
pubmed: 15118162
Chin J Cancer. 2014 Nov;33(11):549-55
pubmed: 25223910
ScientificWorldJournal. 2012;2012:781291
pubmed: 22606062
J Cell Physiol. 2018 Aug;233(8):5537-5549
pubmed: 29266238
Am J Surg Pathol. 2021 Nov 1;45(11):1476-1486
pubmed: 33927156
J Clin Oncol. 2003 Jun 1;21(11):2085-93
pubmed: 12775733
J Cardiovasc Surg (Torino). 2001 Aug;42(4):555-60
pubmed: 11455296
PLoS Genet. 2009 Aug;5(8):e1000602
pubmed: 19680444
Lung Cancer. 2003 Apr;40(1):45-53
pubmed: 12660006
J Mol Diagn. 2001 Feb;3(1):1-10
pubmed: 11227065
J Natl Cancer Inst. 1997 Jun 18;89(12):857-62
pubmed: 9196251
Front Oncol. 2019 Aug 06;9:713
pubmed: 31448229
Mol Pathol. 1999 Apr;52(2):97-103
pubmed: 10474689
Am J Pathol. 2004 Jan;164(1):91-100
pubmed: 14695323
Environ Health. 2012 Nov 22;11:89
pubmed: 23173984
Cancer. 2005 Feb 1;103(3):608-15
pubmed: 15612080
J Immunol. 2002 Nov 15;169(10):6012-9
pubmed: 12421988
Nat Commun. 2019 Jul 16;10(1):3108
pubmed: 31311932
Tob Induc Dis. 2020 Jul 14;18:60
pubmed: 32765200
PLoS One. 2013 Dec 20;8(12):e84919
pubmed: 24376853
J Biomark. 2013;2013:627845
pubmed: 26317020
J Immunol. 2012 May 1;188(9):4654-62
pubmed: 22467650
Zhongguo Fei Ai Za Zhi. 2000 Aug 20;3(4):265-8
pubmed: 20955673
Viruses. 2021 Apr 30;13(5):
pubmed: 33946406
Toxicology. 2021 Nov;463:152994
pubmed: 34678320
Traffic. 2016 Apr;17(4):327-40
pubmed: 26787361
BMC Cancer. 2021 Mar 24;21(1):310
pubmed: 33761896
Br J Cancer. 2001 Jul 6;85(1):14-22
pubmed: 11437396
Am J Clin Pathol. 2000 Aug;114(2):220-6
pubmed: 10941337
Oncotarget. 2016 May 24;7(21):31014-28
pubmed: 27105536
Cancer Res. 2007 Sep 1;67(17):8264-73
pubmed: 17804741
Int J Environ Res Public Health. 2018 May 21;15(5):
pubmed: 29883409
PLoS Pathog. 2016 May 17;12(5):e1005642
pubmed: 27186886
J Pathol. 2015 Jan;235(2):323-33
pubmed: 25251730
CA Cancer J Clin. 2021 May;71(3):209-249
pubmed: 33538338
J Virol. 2008 Apr;82(7):3679-88
pubmed: 18234802
J Thorac Oncol. 2012 Jan;7(1):85-9
pubmed: 22071781
Exp Mol Med. 2015 Jan 23;47:e131
pubmed: 25613728
PLoS Pathog. 2013;9(10):e1003685
pubmed: 24146621
Br J Cancer. 1996 Jan;73(2):148-53
pubmed: 8546899
Lung Cancer. 2017 Aug;110:63-67
pubmed: 28676221
Br J Cancer. 2011 Jul 12;105(2):320-6
pubmed: 21654679
J Pathol. 2001 Nov;195(4):429-34
pubmed: 11745674
Environ Health Perspect. 2012 Aug;120(8):1067-75
pubmed: 22552995
J Med Virol. 2017 Oct;89(10):1844-1851
pubmed: 28543390
Tumour Virus Res. 2021 Dec;12:200218
pubmed: 34052467
Prostate. 2013 Feb 15;73(3):236-41
pubmed: 22851253
Sci Adv. 2021 Jan 29;7(5):
pubmed: 33514539
Toxicol Mech Methods. 2020 Mar;30(3):197-207
pubmed: 31682781
PLoS One. 2016 Aug 30;11(8):e0160996
pubmed: 27575252
J Virol. 2017 Oct 13;91(21):
pubmed: 28835490
Diagn Cytopathol. 2016 Dec;44(12):987-993
pubmed: 27774746
Philos Trans R Soc Lond B Biol Sci. 2017 Oct 19;372(1732):
pubmed: 28893937
Hum Pathol. 1994 Jun;25(6):602-5
pubmed: 8013952
J Virol. 2007 Aug;81(15):7825-32
pubmed: 17459936
Cold Spring Harb Perspect Med. 2017 Jan 3;7(1):
pubmed: 28049655
Am J Pathol. 1993 Nov;143(5):1250-4
pubmed: 8238241
Chin J Cancer. 2014 Dec;33(12):581-90
pubmed: 25418193
Respir Res. 2003;4:12
pubmed: 14641911
Biology (Basel). 2020 Dec 11;9(12):
pubmed: 33322292
Genome. 2008 Dec;51(12):1032-9
pubmed: 19088816
Br J Cancer. 2005 Feb 28;92(4):743-6
pubmed: 15700034
J Med Biochem. 2019 Mar 03;38(2):188-195
pubmed: 30867647
Kaohsiung J Med Sci. 2006 Jan;22(1):14-9
pubmed: 16570563
Nat Rev Cancer. 2014 Aug;14(8):535-46
pubmed: 25056707
Nature. 1992 Mar 26;356(6367):347-50
pubmed: 1312681
Front Immunol. 2020 Apr 03;11:498
pubmed: 32318060
Oncol Lett. 2018 May;15(5):7506-7514
pubmed: 29725457
Medicine (Madr). 2014 Mar;11(50):2954-2964
pubmed: 32287897
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2007 Sep;21(3):288-90
pubmed: 17971949
Indian J Pathol Microbiol. 2013 Oct-Dec;56(4):359-64
pubmed: 24441222
Chemosphere. 2020 Jul;251:126426
pubmed: 32171938
J Pathol. 2007 Jul;212(3):306-15
pubmed: 17534844
Virchows Arch. 2003 Aug;443(2):122-32
pubmed: 12884041
Mol Cancer. 2007 Apr 02;6:24
pubmed: 17407548
Eur Respir J. 2012 Jul;40(1):177-84
pubmed: 22267755
Clin Cancer Res. 2008 May 1;14(9):2570-8
pubmed: 18451218
Oncogene. 2002 Oct 21;21(48):7365-75
pubmed: 12379879
Clin Chest Med. 2011 Dec;32(4):703-40
pubmed: 22054881
Cell. 2018 Apr 5;173(2):283-285
pubmed: 29625045
Int J Cancer. 2017 Nov 1;141(9):1722-1729
pubmed: 28571118
Curr Opin Virol. 2021 Oct;50:147-158
pubmed: 34464845
Acta Biochim Pol. 2017;64(4):641-646
pubmed: 29141053
J Biol Chem. 2006 Jan 13;281(2):1215-23
pubmed: 16257957
Cancer Cell. 2003 Sep;4(3):181-9
pubmed: 14522252
Oncotarget. 2017 Aug 3;8(51):88529-88536
pubmed: 29179454
J Oral Pathol Med. 2008 Nov;37(10):626-33
pubmed: 18710421
Jpn J Cancer Res. 2002 Oct;93(10):1107-13
pubmed: 12417040
IARC Monogr Eval Carcinog Risks Hum. 2010;92:1-853
pubmed: 21141735
PLoS One. 2020 Oct 16;15(10):e0240729
pubmed: 33064745
Front Microbiol. 2018 Mar 16;9:454
pubmed: 29615992
J Virol. 2014 Jun;88(12):6660-71
pubmed: 24696473
Cancer Epidemiol. 2010 Aug;34(4):472-7
pubmed: 20444664
Cancer Cell. 2006 Jul;10(1):25-38
pubmed: 16843263
Int J Cancer. 2016 Nov 1;139(9):1958-66
pubmed: 27380650
Environ Health Perspect. 2016 Apr;124(4):445-51
pubmed: 26372664
Cancers (Basel). 2020 Jul 27;12(8):
pubmed: 32726920
J Pathol. 1994 Dec;174(4):257-65
pubmed: 7884587
Genes Dev. 2013 Mar 1;27(5):504-13
pubmed: 23475959
Viruses. 2021 Apr 18;13(4):
pubmed: 33919628
Immunotargets Ther. 2021 Jun 22;10:185-200
pubmed: 34189130
Mod Pathol. 2009 Apr;22(4):530-7
pubmed: 19252476
Virus Genes. 2010 Jun;40(3):307-19
pubmed: 20162447
Immunogenetics. 2010 Apr;62(4):237-51
pubmed: 20217071
J Cancer Res Clin Oncol. 2019 Nov;145(11):2663-2674
pubmed: 31541338
Sci Rep. 2016 May 18;6:26156
pubmed: 27189712
PLoS Pathog. 2012 Sep;8(9):e1002902
pubmed: 22969425
Proc Natl Acad Sci U S A. 2005 Jan 4;102(1):175-9
pubmed: 15611471
Nat Commun. 2019 Mar 8;10(1):1125
pubmed: 30850589
J Virol. 1999 Mar;73(3):2115-25
pubmed: 9971794
Int J Cancer. 1994 Oct 15;59(2):155-8
pubmed: 7927911
Nat Rev Immunol. 2001 Oct;1(1):75-82
pubmed: 11905817
Oral Dis. 2017 Oct;23(7):897-912
pubmed: 27973759
Cancers (Basel). 2019 May 31;11(6):
pubmed: 31159203
J Natl Cancer Inst. 2004 Nov 17;96(22):1691-702
pubmed: 15547182
Clin Lung Cancer. 2017 Nov;18(6):e395-e402
pubmed: 28550959
Br J Cancer. 2006 May 22;94(10):1452-9
pubmed: 16641908
Front Public Health. 2020 Feb 20;8:14
pubmed: 32154200
Am J Clin Pathol. 2007 Feb;127(2):254-62
pubmed: 17210516
Clin Exp Immunol. 2006 Sep;145(3):469-73
pubmed: 16907915
Oncol Rep. 2009 Apr;21(4):971-5
pubmed: 19287995
PLoS One. 2017 Mar 27;12(3):e0174136
pubmed: 28346502
Nat Microbiol. 2018 Feb;3(2):172-180
pubmed: 29292384
Nicotine Tob Res. 2015 Jul;17(7):825-30
pubmed: 25481919
Transl Lung Cancer Res. 2015 Apr;4(2):110-8
pubmed: 25870793
Cancers (Basel). 2020 Jun 05;12(6):
pubmed: 32517128
Nature. 2007 Aug 2;448(7153):561-6
pubmed: 17625570
Scientifica (Cairo). 2012;2012:438204
pubmed: 24278697
Lung Cancer. 2011 Oct;74(1):139-44
pubmed: 21353324
Mod Pathol. 1996 May;9(5):491-5
pubmed: 8733763
Ann Transl Med. 2020 Sep;8(18):1169
pubmed: 33241018
Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20464-9
pubmed: 19920174
J Radiat Res. 2021 May 12;62(3):556
pubmed: 33899107
Lung Cancer. 1996 Mar;14 Suppl 1:S99-105
pubmed: 8785673
EBioMedicine. 2018 Apr;30:184-191
pubmed: 29606628
Sci Total Environ. 2016 Sep 15;565:1201-1207
pubmed: 27265733
Front Oncol. 2019 Sep 13;9:865
pubmed: 31572673
J Natl Cancer Inst. 1999 Jul 21;91(14):1194-210
pubmed: 10413421
Lung Cancer. 2014 Sep;85(3):373-8
pubmed: 25047676
Digestion. 2021;102(1):25-32
pubmed: 33070127
PLoS One. 2009 Jun 24;4(6):e6029
pubmed: 19551151
Lung Cancer. 2000 Jun;28(3):225-35
pubmed: 10812191
Oncotarget. 2018 Jan 2;9(12):10417-10435
pubmed: 29535816
Oncogene. 2019 Jun;38(24):4669-4684
pubmed: 30745576
Gastroenterology. 2009 Sep;137(3):824-33
pubmed: 19445939
Int J Biol Markers. 2005 Apr-Jun;20(2):87-92
pubmed: 16011038
Future Virol. 2009 Jan;4(1):79-91
pubmed: 25635182
Eur J Cardiothorac Surg. 2003 Jun;23(6):870-7; discussion 877
pubmed: 12829060
Medicine (Baltimore). 2018 Aug;97(35):e11794
pubmed: 30170373
Cancer. 1998 Jun 15;82(12):2334-42
pubmed: 9635525
Environ Health Prev Med. 2021 Aug 13;26(1):80
pubmed: 34388980
Genes Dev. 2001 Dec 15;15(24):3243-8
pubmed: 11751630
Nat Commun. 2015 Mar 11;6:6377
pubmed: 25758528
Infect Agent Cancer. 2021 Jun 30;16(1):50
pubmed: 34193233
Oncology. 1994 Nov-Dec;51(6):544-51
pubmed: 7970501
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2011 Aug;25(4):277-9
pubmed: 22097606
Cancer. 2013 Jun 15;119(12):2268-74
pubmed: 23526491
PLoS One. 2014 Oct 31;9(10):e110617
pubmed: 25360721
J Virol. 1999 Aug;73(8):6964-72
pubmed: 10400795
J Thorac Oncol. 2010 Dec;5(12):1922-32
pubmed: 21155183
J Virol. 2006 Jan;80(2):845-53
pubmed: 16378986
Lancet Oncol. 2015 Apr;16(4):e165-72
pubmed: 25846096
PLoS Pathog. 2013 Feb;9(2):e1003187
pubmed: 23436997
Int J Environ Res Public Health. 2020 Feb 24;17(4):
pubmed: 32102460
J Pathol. 2017 Aug;242(4):391-399
pubmed: 28418084
Curr Top Microbiol Immunol. 2001;258:13-33
pubmed: 11443858
Curr Opin Virol. 2013 Jun;3(3):260-5
pubmed: 23567077
Curr Opin Pulm Med. 2014 Jul;20(4):324-31
pubmed: 24811836
Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):E3473-82
pubmed: 23161911
Am J Surg Pathol. 2019 Feb;43(2):211-219
pubmed: 30334830
Cancer Causes Control. 2010 Jun;21(6):871-7
pubmed: 20155313
Cancers (Basel). 2020 Aug 28;12(9):
pubmed: 32872147
Hum Vaccin Immunother. 2019;15(3):603-610
pubmed: 30380978
Leukemia. 2019 Jun;33(6):1451-1462
pubmed: 30546078
Crit Rev Oncol Hematol. 2016 Mar;99:63-73
pubmed: 26689115
Int J Clin Exp Pathol. 2008 Jan 01;1(3):198-216
pubmed: 18784828
Oncogene. 2003 Aug 11;22(33):5108-21
pubmed: 12910248
J Thorac Dis. 2013 Oct;5 Suppl 5:S479-90
pubmed: 24163741
Int J Exp Pathol. 2001 Jun;82(3):149-70
pubmed: 11488990
Cell. 1989 Jul 14;58(1):5-8
pubmed: 2546674
Zhonghua Bing Li Xue Za Zhi. 1996 Feb;25(1):1-3
pubmed: 8762429
Nat Rev Cancer. 2009 Jun;9(6):400-14
pubmed: 19440234
Lung Cancer. 2001 Nov;34(2):219-26
pubmed: 11679180