Lutein and Zeaxanthin Intake during Pregnancy and Visual Function in Offspring at 11-12 Years of Age.
childhood
contrast sensitivity
lutein
population-based birth cohort
pregnancy
visual acuity
zeaxanthin
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
18 Feb 2022
18 Feb 2022
Historique:
received:
15
01
2022
revised:
03
02
2022
accepted:
16
02
2022
entrez:
26
2
2022
pubmed:
27
2
2022
medline:
3
3
2022
Statut:
epublish
Résumé
(1) Background: Lutein and zeaxanthin (L&Z) are essential dietary nutrients that are a crucial component of the human macula, contributing to visual functioning. They easily cross the placental barrier, so that retinal deposition commences during foetal development. This study aims to assess associations between maternal L&Z intake during pregnancy and offspring visual function at 11-12 years. (2) Methods: Using the Spanish INfancia y Medio Ambiente project (INMA) Sabadell birth cohort, 431 mother-child pairs were analysed. L&Z data were obtained from food frequency questionnaires (FFQ) at week 12 and 32 of pregnancy, alongside other nutritional and sociodemographic covariates. Contrast vision (CS) and visual acuity (VA) were assessed using the automated Freiburg Acuity and Contrast Testing (FRACT) battery. Low CS and VA were defined as being below the 20th cohort centile. Associations were explored using multiple logistic regression. (3) Results: After controlling for potential confounders, L&Z intake during the 1st and 3rd trimester did not reveal any statistically significant association with either CS or VA in offspring at age 11/12 years. (4) Conclusions: No evidence of a long-term association between L&Z intake during pregnancy and visual function in offspring was found. Further larger long-term studies including blood L&Z levels are required to confirm this result.
Identifiants
pubmed: 35215522
pii: nu14040872
doi: 10.3390/nu14040872
pmc: PMC8876686
pii:
doi:
Substances chimiques
Zeaxanthins
0
Lutein
X72A60C9MT
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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