Accurate Measurement and Harmonized Reference Ranges for Total and Free Testosterone Levels.
Ensemble ALlstery Model
Equilibrium dialysis
Free testosterone
Harmonized reference ranges for testosterone
Hypogonadism
Testosterone assays
Testosterone deficiency
Total testosterone
Journal
Endocrinology and metabolism clinics of North America
ISSN: 1558-4410
Titre abrégé: Endocrinol Metab Clin North Am
Pays: United States
ID NLM: 8800104
Informations de publication
Date de publication:
03 2022
03 2022
Historique:
entrez:
26
2
2022
pubmed:
27
2
2022
medline:
1
4
2022
Statut:
ppublish
Résumé
Diagnosing testosterone deficiency requires accurate and precise measurement of total testosterone levels by an accurate method, such as liquid chromatography-tandem mass spectrometry in a laboratory certified by an accuracy-based program (eg, Centers for Disease Control and Prevention's Hormone Standardization (HoST) Program), and, if needed, free testosterone level. Free testosterone level should ideally be measured by equilibrium dialysis method. Testosterone levels should be measured in 2 or more fasting samples obtained in the morning. Harmonized reference ranges for total testosterone can be applied to laboratories that certified by the HoST Program.
Identifiants
pubmed: 35216721
pii: S0889-8529(21)00102-X
doi: 10.1016/j.ecl.2021.11.002
pii:
doi:
Substances chimiques
Testosterone
3XMK78S47O
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
63-75Informations de copyright
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