LC-MS-guided isolation of 2-(2-phenylethyl)chromone dimers from red soil agarwood of Aquilaria crassna.

Chromatography, Liquid Chromones / chemistry Flavonoids / chemistry Humans Molecular Structure Soil Tandem Mass Spectrometry Thymelaeaceae / chemistry Wood / chemistry
2-(2-phenylethyl)chromone dimers Aquilaria crassna Cytotoxicity Red soil agarwood

Journal

Fitoterapia
ISSN: 1873-6971
Titre abrégé: Fitoterapia
Pays: Netherlands
ID NLM: 16930290R

Informations de publication

Date de publication:
Apr 2022
Historique:
received: 03 01 2022
revised: 16 02 2022
accepted: 20 02 2022
pubmed: 27 2 2022
medline: 8 4 2022
entrez: 26 2 2022
Statut: ppublish

Résumé

Six new 2-(2-phenylethyl)chromone dimers (1-6) were isolated from ethyl ether extract of red soil agarwood of Aquilaria crassna from Vietnam by LC-MS-guided fractionation procedure. Their structures were unambiguously elucidated based on HRESIMS, 1D and 2D NMR spectra. The absolute configuration of 2-(2-phenylethyl)chromone dimers was determined by comparison of the experimental and computed ECD spectra. Compound 6 displayed cytotoxicity against the human myeloid leukemia cell line (K562) with an IC

Identifiants

DOI: 10.1016/j.fitote.2022.105162 PMID: 35217119
pubmed: 35217119
pii: S0367-326X(22)00040-5
doi: 10.1016/j.fitote.2022.105162
pii:
doi:

Substances chimiques

Chromones 0
Flavonoids 0
Soil 0
2-(2-phenylethyl)chromone 61828-53-3

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

105162

Informations de copyright

Copyright © 2022 Elsevier B.V. All rights reserved.

Auteurs

Di He (D)

Hainan Engineering Research Center of Agarwood, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.

Wen-Hua Dong (WH)

Hainan Engineering Research Center of Agarwood, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.

Wei Li (W)

Hainan Engineering Research Center of Agarwood, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.

Li Yang (L)

Hainan Engineering Research Center of Agarwood, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.

Jing-Zhe Yuan (JZ)

Hainan Engineering Research Center of Agarwood, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.

Cui-Juan Gai (CJ)

Hainan Engineering Research Center of Agarwood, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.

Cai-Hong Cai (CH)

Hainan Engineering Research Center of Agarwood, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.

Hao-Fu Dai (HF)

Hainan Engineering Research Center of Agarwood, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.

Hao Wang (H)

Hainan Engineering Research Center of Agarwood, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China. Electronic address: wanghao@itbb.org.cn.

Wen-Li Mei (WL)

Hainan Engineering Research Center of Agarwood, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.

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Classifications MeSH

questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Chromatographie › Chromatographie en phase liquide › LC-MS-guided isolation of...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzopyranes › 4H-1-Benzopyran-4-ones › LC-MS-guided isolation of...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzopyranes › 4H-1-Benzopyran-4-ones › Flavonoïdes › LC-MS-guided isolation of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › LC-MS-guided isolation of...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › LC-MS-guided isolation of...
questionsmedicales.fr › Environnement et santé publique › Environnement › Sol › LC-MS-guided isolation of...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Spectrométrie de masse › Spectrométrie de masse en tandem › LC-MS-guided isolation of...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Thymelaeaceae › LC-MS-guided isolation of...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux de construction › Bois › LC-MS-guided isolation of...