Endoscopic Treatment of Sellar Arachnoid Cysts via a Simple Cyst-Opening Technique: Long-Term Outcomes From a Single Center.


Journal

World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275

Informations de publication

Date de publication:
05 2022
Historique:
received: 19 12 2021
revised: 14 02 2022
accepted: 15 02 2022
pubmed: 27 2 2022
medline: 6 5 2022
entrez: 26 2 2022
Statut: ppublish

Résumé

Sellar arachnoid cysts (SACs) are rare lesions that require treatment only if symptomatic. The endoscopic endonasal approach has been widely used. Despite their simple cystic appearance and the straight-forward surgical intervention, important associated risks exist, with cerebrospinal fluid (CSF) leak the prevalent risk. A retrospective analysis of patients with pathologically confirmed SAC between January 2006 and December 2019 was conducted. A homogeneous simple cyst-opening technique and skull base reconstruction with nasoseptal flaps was used. A total of 10 patients were identified (7 women and 3 men; median age, 54.5 years; range, 20-77 years). Of the 10 patients, 8 had had newly diagnosed SACs and 2 patients had had recurrence from a previously microsurgically fenestrated SAC. Eight patients had presented with visual symptoms, one with visual symptoms and fatigue, and one with intractable headaches. Neuro-ophthalmological and endocrinological assessments had revealed visual field deficits in 6, visual acuity decline in 5, and hypopituitarism in 2 patients. The median calculated volume was 1.71 mL (range, 0.27-2.54 mL). Postoperatively, no CSF leak and no further surgical complications were noted. The visual field had improved in 4 of 6 patients and visual acuity had improved in 4 of 5 patients. Anterior pituitary function had improved in 1, worsened in 1, and remained stable in 8 patients. One patient had developed diabetes insipidus. One recurrence was recorded at 54 months postoperatively. The results from the present study have shown that SACs can be effectively treated using a simple cyst-opening technique. The routine use of nasoseptal flaps significantly reduced the risk of CSF leakage without compromising nasal quality of life in the long term or mandating additional incisions. Long-term follow-up is important to monitor for late recurrence.

Sections du résumé

BACKGROUND
Sellar arachnoid cysts (SACs) are rare lesions that require treatment only if symptomatic. The endoscopic endonasal approach has been widely used. Despite their simple cystic appearance and the straight-forward surgical intervention, important associated risks exist, with cerebrospinal fluid (CSF) leak the prevalent risk.
METHODS
A retrospective analysis of patients with pathologically confirmed SAC between January 2006 and December 2019 was conducted. A homogeneous simple cyst-opening technique and skull base reconstruction with nasoseptal flaps was used.
RESULTS
A total of 10 patients were identified (7 women and 3 men; median age, 54.5 years; range, 20-77 years). Of the 10 patients, 8 had had newly diagnosed SACs and 2 patients had had recurrence from a previously microsurgically fenestrated SAC. Eight patients had presented with visual symptoms, one with visual symptoms and fatigue, and one with intractable headaches. Neuro-ophthalmological and endocrinological assessments had revealed visual field deficits in 6, visual acuity decline in 5, and hypopituitarism in 2 patients. The median calculated volume was 1.71 mL (range, 0.27-2.54 mL). Postoperatively, no CSF leak and no further surgical complications were noted. The visual field had improved in 4 of 6 patients and visual acuity had improved in 4 of 5 patients. Anterior pituitary function had improved in 1, worsened in 1, and remained stable in 8 patients. One patient had developed diabetes insipidus. One recurrence was recorded at 54 months postoperatively.
CONCLUSIONS
The results from the present study have shown that SACs can be effectively treated using a simple cyst-opening technique. The routine use of nasoseptal flaps significantly reduced the risk of CSF leakage without compromising nasal quality of life in the long term or mandating additional incisions. Long-term follow-up is important to monitor for late recurrence.

Identifiants

pubmed: 35217229
pii: S1878-8750(22)00219-4
doi: 10.1016/j.wneu.2022.02.072
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e625-e634

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Auteurs

Aristotelis Kalyvas (A)

Division of Neurosurgery, Department of Surgery, University Health Network/Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada. Electronic address: aristoteliskalyvas@gmail.com.

Matthias Milesi (M)

Division of Neurosurgery, Department of Surgery, University Health Network/Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada; Department of Neurosurgery, Medical University of Vienna, Vienna, Austria.

Matheus Leite (M)

Division of Neurosurgery, Department of Surgery, University Health Network/Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.

Kaiyun Yang (K)

Division of Neurosurgery, Department of Surgery, University Health Network/Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.

Leslie St Jacques (L)

Division of Neurosurgery, Department of Surgery, University Health Network/Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.

Allan Vescan (A)

Department of Otolaryngology, Head and Neck Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

Ozgur Mete (O)

Department of Pathology, University Health Network, University of Toronto, Toronto, Ontario, Canada.

Shereen Ezzat (S)

Department of Endocrine Oncology, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada.

Gelareh Zadeh (G)

Division of Neurosurgery, Department of Surgery, University Health Network/Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.

Fred Gentili (F)

Division of Neurosurgery, Department of Surgery, University Health Network/Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.

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