Outcomes of kidney donors with sickle cell trait: A preliminary analysis.
donor
kidney
sickle cell
transplant
Journal
Clinical transplantation
ISSN: 1399-0012
Titre abrégé: Clin Transplant
Pays: Denmark
ID NLM: 8710240
Informations de publication
Date de publication:
06 2022
06 2022
Historique:
revised:
14
02
2022
received:
17
01
2022
accepted:
21
02
2022
pubmed:
27
2
2022
medline:
16
6
2022
entrez:
26
2
2022
Statut:
ppublish
Résumé
Most transplant centers do not screen kidney donor candidates for sickle cell trait (SCT) and many decline candidates with SCT since it may associate with kidney disease. We compared 17 kidney donors with SCT to propensity score matched donor controls on mortality, reduced eGFR, proteinuria and kidney failure. The prevalence of SCT in African American (AA) donors was 11 per 1000 compared to 73 per 1000 in non-donor AA. Donors with SCT were younger; 33 versus 35 years in controls, nine were AA, six were White, and two were listed as other or unknown ethnicities. After a follow-up period of 18.2 ± 10.5 years, the proportions of donors with SCT and controls who were alive, developed hypertension or cardiovascular disease were similar. No donor with SCT developed an eGFR <30 mL/min/1.73 m
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e14626Informations de copyright
© 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
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