Retinometer predicts visual outcome in Descemet membrane endothelial keratoplasty.


Journal

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
ISSN: 1435-702X
Titre abrégé: Graefes Arch Clin Exp Ophthalmol
Pays: Germany
ID NLM: 8205248

Informations de publication

Date de publication:
Jul 2022
Historique:
received: 08 11 2021
accepted: 21 02 2022
revised: 15 02 2022
pubmed: 27 2 2022
medline: 22 6 2022
entrez: 26 2 2022
Statut: ppublish

Résumé

To analyze the preoperative predictive value of retinometer visual acuity (VA) in eyes following Descemet membrane endothelial keratoplasty (DMEK). Patients undergoing DMEK between August 2011 and July 2020 were included. Preoperative interference visual acuity was assessed using Heine Lambda 100 Retinometer. Depending on the presence or absence of concomitant ocular disease, the Retinometer was evaluated for its ability to preoperatively predict best-corrected visual acuity (BCVA) six months after surgery using correlation, simple and multiple linear regression, contingency analyses, and receiver operating characteristic (ROC) analysis. Preoperative corneal backscatter was correlated with Retinometer prediction accuracy. A total of 198 eyes were included in the analysis. There was a significant correlation between Retinometer VA and postoperative BCVA (r = 0.647, P < 0.001). Regardless of the presence or absence of concomitant ocular disease and the surgery procedure (DMEK & triple DMEK), Retinometer VA was the most significant predictor of postoperative BCVA (P < 0.001). ROC analysis revealed reliable diagnostic performance of the Retinometer (AUC = 0.829, P < 0.001). A Retinometer VA ≥ 0.5 accurately predicted a postoperative BCVA ≥ 0.5 in 91% of cases. No association was found between corneal backscatter and prediction accuracy (P = 0.566). Retinometer VA can be used for preoperative prediction of postoperative BCVA in DMEK and triple DMEK patients, independent of increased backscatter values and the presence or absence of concomitant ocular disease. By using this simple but effective tool, indication for DMEK can be facilitated and postoperative outcomes can be realistically predicted preoperatively.

Identifiants

pubmed: 35218379
doi: 10.1007/s00417-022-05605-w
pii: 10.1007/s00417-022-05605-w
pmc: PMC9203399
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2283-2290

Informations de copyright

© 2022. The Author(s).

Références

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Auteurs

Caroline Sophie Wald (CS)

Department of Ophthalmology, University of Leipzig Medical Center, Liebigstrasse 10-14, 04103, Leipzig, Germany.

Jan Darius Unterlauft (JD)

University Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland.

Matus Rehak (M)

Department of Ophthalmology, University Hospital of Gießen and Marburg, Gießen, Germany.

Christian Girbardt (C)

Department of Ophthalmology, University of Leipzig Medical Center, Liebigstrasse 10-14, 04103, Leipzig, Germany. christian.girbardt@medizin.uni-leipzig.de.

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