Assessing Tumor-Infiltrating Lymphocytes in Breast Cancer: A Proposal for Combining Immunohistochemistry and Gene Expression Analysis to Refine Scoring.

breast cancer gene expression profiling immunohistochemistry immunotherapy targets tumor-infiltrating lymphocyte

Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2022
Historique:
received: 13 10 2021
accepted: 06 01 2022
entrez: 28 2 2022
pubmed: 1 3 2022
medline: 9 4 2022
Statut: epublish

Résumé

Scoring of tumor-infiltrating lymphocytes (TILs) in breast cancer specimens has gained increasing attention, as TILs have prognostic and predictive value in HER2

Identifiants

pubmed: 35222378
doi: 10.3389/fimmu.2022.794175
pmc: PMC8876933
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

794175

Informations de copyright

Copyright © 2022 Locy, Verhulst, Cools, Waelput, Brock, Cras, Schiettecatte, Jonckheere, van Grunsven, Vanhoeij, Thielemans and Breckpot.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Hanne Locy (H)

Laboratory for Molecular and Cellular Therapy, Department of Biomedical Sciences (BMWE), Vrije Universiteit Brussel (VUB), Brussels, Belgium.

Stefaan Verhulst (S)

Liver Cell Biology Research Group, BMWE, VUB, Brussels, Belgium.

Wilfried Cools (W)

Interfaculty Center Data processing and Statistics, VUB, Brussels, Belgium.

Wim Waelput (W)

Department of Anatomo-Pathology, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium.

Stefanie Brock (S)

Department of Anatomo-Pathology, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium.

Louise Cras (L)

Department of Anatomo-Pathology, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium.

Ann Schiettecatte (A)

Department of Radiology, UZ Brussel, Brussels, Belgium.

Jan Jonckheere (J)

Department of Radiology, UZ Brussel, Brussels, Belgium.

Leo A van Grunsven (LA)

Liver Cell Biology Research Group, BMWE, VUB, Brussels, Belgium.

Marian Vanhoeij (M)

Department of Surgery, UZ Brussel, Brussels, Belgium.

Kris Thielemans (K)

Laboratory for Molecular and Cellular Therapy, Department of Biomedical Sciences (BMWE), Vrije Universiteit Brussel (VUB), Brussels, Belgium.

Karine Breckpot (K)

Laboratory for Molecular and Cellular Therapy, Department of Biomedical Sciences (BMWE), Vrije Universiteit Brussel (VUB), Brussels, Belgium.

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