Case Report: Persistency Pneumococcal Polysaccharide in Cerebrospinal Fluid During a Post Pneumococcal Chronic Aseptic Meningitis: Coincidental or (Auto-)Inflammatory Embers.

aseptic meningitis chronic aseptic meningitis innate immunity pneumococcal cell wall components pneumococcal meningitis

Journal

Frontiers in pediatrics
ISSN: 2296-2360
Titre abrégé: Front Pediatr
Pays: Switzerland
ID NLM: 101615492

Informations de publication

Date de publication:
2022
Historique:
received: 21 08 2021
accepted: 10 01 2022
entrez: 28 2 2022
pubmed: 1 3 2022
medline: 1 3 2022
Statut: epublish

Résumé

We report the case of a 9-months-old boy that has presented a steroid-dependent post-pneumococcal chronic aseptic meningitis was associated with persistence of pneumococcal cell wall components in cerebrospinal fluid during more than 20 months. Suggesting that this antigenic persistence could be involved in post-infectious manifestations through innate immunity response.

Identifiants

pubmed: 35223689
doi: 10.3389/fped.2022.762457
pmc: PMC8864159
doi:

Types de publication

Case Reports

Langues

eng

Pagination

762457

Informations de copyright

Copyright © 2022 Ladeveze, Dumont, Boursier, Batteux, Mahe, Bensimon Borrull, Sarrabay, Bollore, Tuaillon, Godreuil and Jeziorski.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Manon Ladeveze (M)

Département Urgences Post-Urgences, CEREMAIA, CHU de Montpellier, Montpellier, France.

Yann Dumont (Y)

Laboratoire de Bactériologie, CHU de Montpellier, Montpellier, France.

G Boursier (G)

Laboratoire de Génétique des Maladies Rares et Autoinflammatoires, Département de Génétique Médicale, Maladies Rares et Médecine Personnalisée, CEREMAIA, CHU de Montpellier, Univ Montpellier, Montpellier, France.

Frederic Batteux (F)

Plateforme d'ImmunoMonitoring Vaccinal (PIMV), Laboratoire d'Immunologie, Hôpital Cochin, Paris, France.

Perrine Mahe (P)

Département Urgences Post-Urgences, CEREMAIA, CHU de Montpellier, Montpellier, France.

Aurelie Bensimon Borrull (A)

Plateforme d'ImmunoMonitoring Vaccinal (PIMV), Laboratoire d'Immunologie, Hôpital Cochin, Paris, France.

Guillaume Sarrabay (G)

Laboratoire de Génétique des Maladies Rares et Autoinflammatoires, Département de Génétique Médicale, Maladies Rares et Médecine Personnalisée, CEREMAIA, CHU de Montpellier, Univ Montpellier, Montpellier, France.

Karine Bollore (K)

Plateforme Exploration de cellules rares en immunologie et infectiologie, CHU de Montpellier, Montpellier, France.
PCCEI, INSERM, Univ Montpellier, Montpellier, France.

Edouard Tuaillon (E)

Plateforme Exploration de cellules rares en immunologie et infectiologie, CHU de Montpellier, Montpellier, France.
PCCEI, INSERM, Univ Montpellier, Montpellier, France.
Laboratoire de virologie, CHU de Montpellier, Montpellier, France.

Sylvain Godreuil (S)

Laboratoire de Bactériologie, CHU de Montpellier, Montpellier, France.
UMR IRD224-CNRS5290-UM MIVEGEC, Univ Montpellier, Montpellier, France.

Eric Jeziorski (E)

Département Urgences Post-Urgences, CEREMAIA, CHU de Montpellier, Montpellier, France.
PCCEI, INSERM, Univ Montpellier, Montpellier, France.

Classifications MeSH