Dietary Vitamins A, C, and Potassium Intake Is Associated With Narrower Retinal Venular Caliber.
nutrient
potassium
retinal vascular caliber
vitamin A
vitamin C
Journal
Frontiers in medicine
ISSN: 2296-858X
Titre abrégé: Front Med (Lausanne)
Pays: Switzerland
ID NLM: 101648047
Informations de publication
Date de publication:
2022
2022
Historique:
received:
19
11
2021
accepted:
11
01
2022
entrez:
28
2
2022
pubmed:
1
3
2022
medline:
1
3
2022
Statut:
epublish
Résumé
The retinal vasculature, a surrogate for the systemic microvasculature, can be observed non-invasively, providing an opportunity to examine the effects of modifiable factors, such as nutrient intake, on microcirculation. We aimed to investigate the possible associations of dietary nutrient intake with the retinal vessel caliber. In this cross-sectional study, a total of 584 participants in a medical survey of Japanese descendants living in Los Angeles in 2015 underwent a dietary assessment, fundus photographic examination, and comprehensive physical and blood examinations. Retinal vessel caliber was measured using fundus photographs with a semi-automated computer system and summarized as central retinal artery and vein equivalents (CRAE and CRVE). The association between dietary nutrient intake and retinal vessel caliber was analyzed using a multivariate linear regression model adjusted for two models including potential confounders. The first model was adjusted for age and sex. The second model was adjusted for age, sex, smoking status, body mass index, hypertension, diabetes, dyslipidemia, history of coronary heart disease, and history of stroke. After adjustment of potential confounders, compared to the quartile with the lowest intake, the difference in CRVE for the highest quartile was -5.33 μm [95% confidence interval (CI): -9.91 to -0.76, A significant association was observed between higher vitamins A, C and potassium intakes and narrower retinal venular caliber.
Identifiants
pubmed: 35223917
doi: 10.3389/fmed.2022.818139
pmc: PMC8866761
doi:
Types de publication
Journal Article
Langues
eng
Pagination
818139Informations de copyright
Copyright © 2022 Edo, Ibrahim, Hirooka, Toda, Kamaruddin, Kawano, Nagao, Ohno, Yoneda and Kiuchi.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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