Short-Term Supplementation With Fermented Red Clover Extract Reduces Vascular Inflammation in Early Post-menopausal Women.
cardiovascular health
fermented red clover
isoflavones
phytoestrogen
post-menopausal women
skeletal muscle microcirculation
supplementation
vascular inflammation
Journal
Frontiers in cardiovascular medicine
ISSN: 2297-055X
Titre abrégé: Front Cardiovasc Med
Pays: Switzerland
ID NLM: 101653388
Informations de publication
Date de publication:
2022
2022
Historique:
received:
01
12
2021
accepted:
19
01
2022
entrez:
28
2
2022
pubmed:
1
3
2022
medline:
1
3
2022
Statut:
epublish
Résumé
The decline in estrogen at menopause poses a critical challenge to cardiovascular and metabolic health. Recently, a growing interest in the role of phytoestrogens, with a particular focus on isoflavones, has emerged as they can bind to estrogen receptors and may mimic the roles of endogenous estrogen. Fermented red clover extract (RC) contains isoflavones with superior bioavailability compared to non-fermented isoflavones, however little is known regarding the impact of isoflavones on cardiovascular and metabolic health. We assessed markers of vascular health in plasma and skeletal muscle samples obtained from healthy but sedentary early post-menopausal women (
Identifiants
pubmed: 35224058
doi: 10.3389/fcvm.2022.826959
pmc: PMC8866445
doi:
Types de publication
Journal Article
Langues
eng
Pagination
826959Informations de copyright
Copyright © 2022 Wickham, Nørregaard, Oxfeldt, Cheung, Gliemann, Hansen and Hellsten.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The reviewer PJ declared a shared affiliation with several of the authors MH and MO, to the handling editor at time of review.
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