Mediastinal Fibrosarcoma in a Dog-Case Report.
blunt dissection
case report
chemotherapy
dog
doxorubicin
fibrosarcoma
mediastinum
surgery
Journal
Frontiers in veterinary science
ISSN: 2297-1769
Titre abrégé: Front Vet Sci
Pays: Switzerland
ID NLM: 101666658
Informations de publication
Date de publication:
2022
2022
Historique:
received:
23
11
2021
accepted:
13
01
2022
entrez:
28
2
2022
pubmed:
1
3
2022
medline:
1
3
2022
Statut:
epublish
Résumé
This represents the first published case report of mediastinal fibrosarcoma in a dog. An 8-year-old male neutered mixed breed dog was presented for evaluation of lethargy and increased panting. Thoracic focused assessment with sonography for trauma revealed moderate pleural effusion. Thoracic radiograph findings were suggestive of a cranial mediastinal mass. Computed tomography revealed a mass within the right ventral aspect of the cranial mediastinum. On surgical exploration, a cranial mediastinal mass with an adhesion to the right cranial lung lobe was identified and removed en-bloc using a vessel sealant device and requiring a partial lung lobectomy. Histopathology results described the cranial mediastinal mass as fibrosarcoma with reactive mesothelial cells identified within the sternal lymph node. The patient was treated with systemic chemotherapy following surgical removal. To date, the dog has survived 223 days following diagnosis with recurrence noted 161 days following diagnosis and radiation therapy was initiated. Primary cranial mediastinal fibrosarcoma while a seemingly rare cause of thoracic pathology in dogs, should be considered in the differential diagnosis for a cranial mediastinal mass.
Identifiants
pubmed: 35224085
doi: 10.3389/fvets.2022.820956
pmc: PMC8863873
doi:
Types de publication
Case Reports
Langues
eng
Pagination
820956Informations de copyright
Copyright © 2022 McGrath, Salyer, Seelmann, Lundberg, Leonard, Lorbach, Lumbrezer-Johnson, Hostnik, Tremolada, Lapsley and Selmic.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
J Small Anim Pract. 2009 Nov;50(11):568-74
pubmed: 19814769
Clin Tech Small Anim Pract. 1998 Feb;13(1):47-52
pubmed: 9634348
Vet Pathol. 1978 Jan;15(1):55-63
pubmed: 625869
Vet Surg. 2014 Oct;43(7):774-82
pubmed: 24724565
J Vet Intern Med. 2000 Nov-Dec;14(6):578-82
pubmed: 11110377
Vet Radiol Ultrasound. 2020 Jul;61(4):385-393
pubmed: 32400045
Vet Radiol Ultrasound. 2020 Jan;61(1):25-32
pubmed: 31574584
J Small Anim Pract. 2020 Jun;61(6):338-345
pubmed: 32323304
Cancer. 2008 Aug 1;113(3):573-81
pubmed: 18521899
Aust Vet J. 2003 Dec;81(12):732-8
pubmed: 15080482
J Am Vet Med Assoc. 1997 Nov 1;211(9):1147-51
pubmed: 9364229
Vet Clin Pathol. 2006 Mar;35(1):24-30
pubmed: 16511787
Vet Comp Oncol. 2008 Mar;6(1):19-30
pubmed: 19178660
J Am Vet Med Assoc. 2006 Apr 1;228(7):1053-62
pubmed: 16579784
Ir Vet J. 2014 Jul 27;67(1):15
pubmed: 25089185
Lancet Oncol. 2004 Feb;5(2):107-18
pubmed: 14761815
Radiographics. 2002 May-Jun;22(3):621-37
pubmed: 12006691
Cancer Cytopathol. 2010 Apr 25;118(2):90-6
pubmed: 20209622
Vet Clin North Am Small Anim Pract. 1985 May;15(3):557-67
pubmed: 3892869
J Am Vet Med Assoc. 1989 Dec 1;195(11):1580-3
pubmed: 2599941
J Small Anim Pract. 2014 Jan;55(1):28-32
pubmed: 24329599
Hum Pathol. 1998 Apr;29(4):339-46
pubmed: 9563782
Top Companion Anim Med. 2021 Mar;42:100494
pubmed: 33221543
Vet Radiol Ultrasound. 2004 Nov-Dec;45(6):542-6
pubmed: 15605846
Vet Rec. 2007 Mar 10;160(10):321-6
pubmed: 17351172
Vet Radiol Ultrasound. 2019 May;60(3):289-299
pubmed: 30557908
J Am Vet Med Assoc. 2007 Feb 15;230(4):548-54
pubmed: 17302554
Am J Clin Pathol. 1990 Jun;93(6):741-8
pubmed: 2161177
Vet Comp Oncol. 2016 Dec;14(4):e135-e145
pubmed: 25393921
J Am Vet Med Assoc. 2000 Jul 15;217(2):205-10
pubmed: 10909459