Sexual function after hysterectomy according to surgical indication: a prospective cohort study.


Journal

Sexual health
ISSN: 1449-8987
Titre abrégé: Sex Health
Pays: Australia
ID NLM: 101242667

Informations de publication

Date de publication:
03 2022
Historique:
received: 17 08 2021
accepted: 19 01 2022
pubmed: 1 3 2022
medline: 6 5 2022
entrez: 28 2 2022
Statut: ppublish

Résumé

Our aims were to describe characteristics of sexual function prior to and 6months following benign hysterectomy in patients with three common surgical indications, and to identify preoperative factors that influence the magnitude and direction of change in sexual function after the procedure. This prospective observational cohort study enrolled women (n =80) undergoing hysterectomy for benign indications. Patients were categorised into three groups according to surgical indication: (1) pelvic pain (PP), (2) abnormal uterine bleeding (AUB), and (3) pelvic organ prolapse (POP). Primary outcome was Female Sexual Function Index (FSFI), which patients completed preoperatively and 6months postoperatively. The study included 80 patients, of whom 25.0% (n =20) had surgical indication of PP, 46.3% (n =37) of AUB, and 28.7% (n =23) of POP. PP patients experienced a significant improvement in overall sexual function, as well as orgasm and pain domains following hysterectomy. Significant improvements were not found in AUB and POP patients. In multivariate analysis, lower baseline sexual function (P <0.001), younger age (P =0.013), and pelvic pain<6months (P =0.020) were each independently associated with improvement in sexual function, but surgical indication was not significant. Individual patient factors including younger age, lower baseline sexual function, and short duration of pelvic pain are associated with a higher likelihood of improvement in sexual function after hysterectomy. Surgical indication does not appear to be predictive of postoperative sexual function once accounting for other factors.

Sections du résumé

BACKGROUND
Our aims were to describe characteristics of sexual function prior to and 6months following benign hysterectomy in patients with three common surgical indications, and to identify preoperative factors that influence the magnitude and direction of change in sexual function after the procedure.
METHODS
This prospective observational cohort study enrolled women (n =80) undergoing hysterectomy for benign indications. Patients were categorised into three groups according to surgical indication: (1) pelvic pain (PP), (2) abnormal uterine bleeding (AUB), and (3) pelvic organ prolapse (POP). Primary outcome was Female Sexual Function Index (FSFI), which patients completed preoperatively and 6months postoperatively.
RESULTS
The study included 80 patients, of whom 25.0% (n =20) had surgical indication of PP, 46.3% (n =37) of AUB, and 28.7% (n =23) of POP. PP patients experienced a significant improvement in overall sexual function, as well as orgasm and pain domains following hysterectomy. Significant improvements were not found in AUB and POP patients. In multivariate analysis, lower baseline sexual function (P <0.001), younger age (P =0.013), and pelvic pain<6months (P =0.020) were each independently associated with improvement in sexual function, but surgical indication was not significant.
CONCLUSION
Individual patient factors including younger age, lower baseline sexual function, and short duration of pelvic pain are associated with a higher likelihood of improvement in sexual function after hysterectomy. Surgical indication does not appear to be predictive of postoperative sexual function once accounting for other factors.

Identifiants

pubmed: 35226836
pii: SH21153
doi: 10.1071/SH21153
pmc: PMC9297198
mid: NIHMS1822054
doi:

Types de publication

Journal Article Observational Study Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

46-54

Subventions

Organisme : NIDA NIH HHS
ID : R01 DA038261
Pays : United States
Organisme : NIAMS NIH HHS
ID : R01 AR060392
Pays : United States
Organisme : NICHD NIH HHS
ID : R01 HD088712
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA042859
Pays : United States
Organisme : NICHD NIH HHS
ID : K23 HD099283
Pays : United States
Organisme : NIDA NIH HHS
ID : R43 DA046981
Pays : United States

Références

Med Sci Monit. 2008 Jan;14(1):CR24-31
pubmed: 18160941
Biol Psychiatry. 2018 Nov 15;84(10):734-742
pubmed: 28258747
J Rheumatol. 2011 Jun;38(6):1113-22
pubmed: 21285161
J Clin Epidemiol. 2010 Nov;63(11):1179-94
pubmed: 20685078
J Obstet Gynaecol. 2012 Feb;32(2):180-4
pubmed: 22296433
J Sex Med. 2014 Sep;11(9):2342-50
pubmed: 25042204
Obstet Gynecol. 2004 Oct;104(4):701-9
pubmed: 15458889
J Psychosom Obstet Gynaecol. 2002 Mar;23(1):51-9
pubmed: 12061038
J Minim Invasive Gynecol. 2016 Sep-Oct;23(6):986-93
pubmed: 27426680
Fertil Steril. 1997 May;67(5):815-6
pubmed: 9130883
Am J Obstet Gynecol. 2018 Jan;218(1):114.e1-114.e12
pubmed: 29031895
Am J Obstet Gynecol. 2004 May;190(5):1416-8
pubmed: 15167854
Fertil Steril. 1994 Nov;62(5):984-8
pubmed: 7926146
Arch Gynecol Obstet. 2017 Sep;296(3):513-518
pubmed: 28685227
J Sex Res. 2010 Nov;47(6):513-27
pubmed: 19705325
Obstet Gynecol. 2010 Mar;115(3):543-551
pubmed: 20177285
Obstet Gynecol. 2002 Feb;99(2):229-34
pubmed: 11814502
J Sex Med. 2010 Feb;7(2 Pt 2):896-904
pubmed: 19889146
J Sex Marital Ther. 2005 Jan-Feb;31(1):1-20
pubmed: 15841702
Pak J Med Sci. 2015;31(3):700-5
pubmed: 26150871
Eur J Obstet Gynecol Reprod Biol. 2015 Dec;195:67-71
pubmed: 26479433
Maturitas. 2011 Apr;68(4):387-90
pubmed: 21237590
Cancer. 2012 Sep 15;118(18):4606-18
pubmed: 22359250
Maturitas. 2008 Dec 20;61(4):358-63
pubmed: 18977621
Int J Gynaecol Obstet. 2014 Feb;124(2):169-73
pubmed: 24290537
J Minim Invasive Gynecol. 2014 Jul-Aug;21(4):567-75
pubmed: 24576505
Hum Reprod. 2011 Nov;26(11):3078-84
pubmed: 21900393
Obstet Gynecol. 2008 Mar;111(3):753-67
pubmed: 18310381
Curr Opin Urol. 2013 Nov;23(6):554-9
pubmed: 24080806
Climacteric. 2009 Jun;12(3):213-21
pubmed: 19117186
JAMA. 1999 Nov 24;282(20):1934-41
pubmed: 10580459
J Sex Marital Ther. 2007 May-Jun;33(3):217-24
pubmed: 17454519

Auteurs

Sara R Till (SR)

Department of Obstetrics and Gynecology, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA; and Chronic Pain and Fatigue Research Center, University of Michigan, 24 Frank Lloyd Wright Drive, Ann Arbor, MI 48105, USA.

Andrew Schrepf (A)

Department of Anesthesiology, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA; and Chronic Pain and Fatigue Research Center, University of Michigan, 24 Frank Lloyd Wright Drive, Ann Arbor, MI 48105, USA.

Jennifer Pierce (J)

Department of Anesthesiology, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.

Stephanie Moser (S)

Department of Anesthesiology, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.

Ellen Kolarik (E)

Department of Anesthesiology, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.

Chad Brummett (C)

Department of Anesthesiology, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA; and Chronic Pain and Fatigue Research Center, University of Michigan, 24 Frank Lloyd Wright Drive, Ann Arbor, MI 48105, USA.

Sawsan As-Sanie (S)

Department of Obstetrics and Gynecology, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA; and Chronic Pain and Fatigue Research Center, University of Michigan, 24 Frank Lloyd Wright Drive, Ann Arbor, MI 48105, USA.

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Classifications MeSH