Aseptic Meningitis after Amenamevir Treatment for Herpes Zoster in the First Branch of the Trigeminal Nerve.
amenamevir
aseptic meningitis
central nervous system infection
varicella zoster virus
Journal
Internal medicine (Tokyo, Japan)
ISSN: 1349-7235
Titre abrégé: Intern Med
Pays: Japan
ID NLM: 9204241
Informations de publication
Date de publication:
15 Sep 2022
15 Sep 2022
Historique:
pubmed:
2
3
2022
medline:
17
9
2022
entrez:
1
3
2022
Statut:
ppublish
Résumé
Amenamevir has been approved for the treatment of herpes zoster (HZ); however, its therapeutic efficacy against central nervous system (CNS) infection may be insufficient due to its low spinal fluid permeability. We herein report a case of aseptic meningitis in a 91-year-old Japanese man treated with amenamevir for HZ in the trigeminal nerve region. Several cases of CNS infection have been reported in patients receiving amenamevir treatment for HZ. Patients with CNS complications often have skin rashes near the trigeminal region. Thus, we should be alert for signs of CNS infection when administering amenamevir to patients with such rashes.
Identifiants
pubmed: 35228415
doi: 10.2169/internalmedicine.8581-21
pmc: PMC9556230
doi:
Substances chimiques
ASP2151
0
Antiviral Agents
0
Oxadiazoles
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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