Serological survey of anti-Leptospira spp. antibodies in individuals with animal hoarding disorder and their dogs in a major city of Southern Brazil.
One Health
hoarding disorder
leptospirosis
sentinel surveillance
Journal
Veterinary medicine and science
ISSN: 2053-1095
Titre abrégé: Vet Med Sci
Pays: England
ID NLM: 101678837
Informations de publication
Date de publication:
03 2022
03 2022
Historique:
pubmed:
2
3
2022
medline:
22
4
2022
entrez:
1
3
2022
Statut:
ppublish
Résumé
Individuals with hoarding disorder (HD) presented a persistent difficulty in detaching from objects and/or animals. Unhealthy conditions, frequently found in cases of animal HD (AHD), may favour environmental contamination and the spread of zoonotic pathogens. Despite that, only one study of zoonotic diseases in individuals with AHD and their companion animals has been conducted to date. This study aimed to assess the seroprevalence of anti-Leptospira spp. antibodies in individuals with AHD and their dogs in a major city of Southern Brazil. Blood samples were obtained from 264 dogs (21 households) and 19 individuals with AHD (11 households) and tested by microscopic agglutination test. All human samples were seronegative. Seropositivity was found in 16/264 (6.1%; CI 95% 3.3-9.6%) dogs from 11/21 (52.38%) households, with titres ranging from 100 up to 400, and Copenhageni (10/16; 62.5%) was the most frequent serovar. Surprisingly, seropositivity of hoarded dogs found herein was among the lowest reportedly observed in other dog populations of Brazil. Two epidemiological variables were significantly associated with seropositivity in dogs: the presence of cat hoarding (p = 0.004) and the report of flood occurrence in the household (p = 0.031). No individuals with AHD were seropositive, and besides the lower seroprevalence of dogs, they probably had contact with Leptospira spp. at some point in their life. Since dogs can be considered potential sentinels in leptospirosis, public health programs must become aware of the risk of leptospirosis cases in households of individuals with AHD and nearby communities.
Sections du résumé
BACKGROUND
Individuals with hoarding disorder (HD) presented a persistent difficulty in detaching from objects and/or animals. Unhealthy conditions, frequently found in cases of animal HD (AHD), may favour environmental contamination and the spread of zoonotic pathogens. Despite that, only one study of zoonotic diseases in individuals with AHD and their companion animals has been conducted to date.
OBJECTIVES
This study aimed to assess the seroprevalence of anti-Leptospira spp. antibodies in individuals with AHD and their dogs in a major city of Southern Brazil.
METHODS
Blood samples were obtained from 264 dogs (21 households) and 19 individuals with AHD (11 households) and tested by microscopic agglutination test.
RESULTS
All human samples were seronegative. Seropositivity was found in 16/264 (6.1%; CI 95% 3.3-9.6%) dogs from 11/21 (52.38%) households, with titres ranging from 100 up to 400, and Copenhageni (10/16; 62.5%) was the most frequent serovar. Surprisingly, seropositivity of hoarded dogs found herein was among the lowest reportedly observed in other dog populations of Brazil. Two epidemiological variables were significantly associated with seropositivity in dogs: the presence of cat hoarding (p = 0.004) and the report of flood occurrence in the household (p = 0.031).
CONCLUSIONS
No individuals with AHD were seropositive, and besides the lower seroprevalence of dogs, they probably had contact with Leptospira spp. at some point in their life. Since dogs can be considered potential sentinels in leptospirosis, public health programs must become aware of the risk of leptospirosis cases in households of individuals with AHD and nearby communities.
Identifiants
pubmed: 35229486
doi: 10.1002/vms3.704
pmc: PMC8959303
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
530-536Informations de copyright
© 2022 The Authors. Veterinary Medicine and Science published by John Wiley & Sons Ltd.
Références
Rev Soc Bras Med Trop. 2013 Nov-Dec;46(6):772-5
pubmed: 24474022
J Venom Anim Toxins Incl Trop Dis. 2013 Sep 25;19(1):23
pubmed: 24066949
Vet Med Sci. 2022 Mar;8(2):530-536
pubmed: 35229486
PLoS Negl Trop Dis. 2015 Nov 12;9(11):e0004095
pubmed: 26562157
Prev Vet Med. 2012 Sep 1;106(1):79-84
pubmed: 22510215
Acta Trop. 2008 Oct;108(1):1-5
pubmed: 18721789
PLoS One. 2020 May 15;15(5):e0233305
pubmed: 32413075
Epidemiol Infect. 2012 Feb;140(2):207-8; author reply 208-9
pubmed: 21396149
Rev Bras Parasitol Vet. 2019 Aug 01;28(3):383-394
pubmed: 31390432
Vet Sci. 2018 Sep 21;5(4):
pubmed: 30248931
Rev Soc Bras Med Trop. 2012 Feb;45(1):100-5
pubmed: 22370837
Trop Med Infect Dis. 2019 Feb 27;4(1):
pubmed: 30818803
Behav Sci Law. 2018 Nov;36(6):698-716
pubmed: 30191593
J Microbiol Methods. 2012 Sep;90(3):321-6
pubmed: 22713608
Rev Argent Microbiol. 2019 Oct - Dec;51(4):324-333
pubmed: 30979517
Front Vet Sci. 2021 Jan 08;7:580400
pubmed: 33490126
J Elder Abuse Negl. 2009 Oct;21(4):307-24
pubmed: 20183137
Cad Saude Publica. 2017 Mar 30;33(2):e00001316
pubmed: 28380121
Zoonoses Public Health. 2016 Jun;63(4):328-36
pubmed: 26515048
Rev Cubana Med Trop. 2005 Jan-Apr;57(1):61-2
pubmed: 17966484
Travel Med Infect Dis. 2017 Jul - Aug;18:46-52
pubmed: 28743546
Rev Soc Bras Med Trop. 2015 Jan-Feb;48(1):50-5
pubmed: 25860464
Public Health Rep. 1999 Jan-Feb;114(1):81-7
pubmed: 9925176
Vet Microbiol. 2010 Jan 27;140(3-4):287-96
pubmed: 19345023
PLoS One. 2019 May 29;14(5):e0217643
pubmed: 31141558
Prev Vet Med. 2020 Aug;181:105037
pubmed: 32590226
PLoS One. 2021 Jan 20;16(1):e0245441
pubmed: 33471855