Engineering a multi-target therapy nanoplatform against tumor growth and metastasis

Anti-Inflammatory Agents, Non-Steroidal / pharmacology Antineoplastic Agents / pharmacology Cell Line, Tumor Cisplatin Humans Neoplasms / drug therapy Prodrugs / pharmacology

Journal

Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838

Informations de publication

Date de publication:
18 Mar 2022
Historique:
pubmed: 2 3 2022
medline: 23 3 2022
entrez: 1 3 2022
Statut: epublish

Résumé

Tumor growth and metastasis are caused by many factors. The complexity means that a multi-target combination therapy strategy should be selected against tumor growth and metastasis. Here, cisplatin (CDDP) and bendazac (Ben) were designed as a novel NSAID-Pt(IV) nanoplatform, which is an effective weapon for combating tumor growth and metastasis.

Identifiants

DOI: 10.1039/d1cc06385e PMID: 35229844
pubmed: 35229844
doi: 10.1039/d1cc06385e
doi:

Substances chimiques

Anti-Inflammatory Agents, Non-Steroidal 0
Antineoplastic Agents 0
Prodrugs 0
Cisplatin Q20Q21Q62J

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3803-3806

Auteurs

Di Zhang (D)

Department of Pharmacy, Shandong Second Provincial General Hospital, 4 West Duanxing Road, Jinan, Shandong Province 250022, China. wujiyongsdcn@gmail.com.

Jing Nie (J)

Department of Pharmacy, Shandong Second Provincial General Hospital, 4 West Duanxing Road, Jinan, Shandong Province 250022, China. wujiyongsdcn@gmail.com.

Dongbo Wang (D)

Department of Pharmacy, Shandong Second Provincial General Hospital, 4 West Duanxing Road, Jinan, Shandong Province 250022, China. wujiyongsdcn@gmail.com.

Huina Wu (H)

Department of Pharmacy, Shandong Second Provincial General Hospital, 4 West Duanxing Road, Jinan, Shandong Province 250022, China. wujiyongsdcn@gmail.com.

Lei Sun (L)

Department of Pharmacy, Shandong Second Provincial General Hospital, 4 West Duanxing Road, Jinan, Shandong Province 250022, China. wujiyongsdcn@gmail.com.

Xuejian Wang (X)

School of Pharmacy, Weifang Medical University, Weifang, Shandong Province 261053, China.

Jiyong Wu (J)

Department of Pharmacy, Shandong Second Provincial General Hospital, 4 West Duanxing Road, Jinan, Shandong Province 250022, China. wujiyongsdcn@gmail.com.
ORCID: 0000-0001-9360-090X

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antirhumatismaux › Anti-inflammatoires non stéroïdiens › Engineering a multi-target therapy...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › Engineering a multi-target therapy...
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Engineering a multi-target therapy...
questionsmedicales.fr › Produits chimiques inorganiques › Composés du platine › Cisplatine › Engineering a multi-target therapy...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Engineering a multi-target therapy...
questionsmedicales.fr › Tumeurs › Engineering a multi-target therapy...
questionsmedicales.fr › Préparations pharmaceutiques › Promédicaments › Engineering a multi-target therapy...