Validation of a post-mortem computed tomography method for age estimation based on the 4th rib in a French population.

Age Determination by Skeleton / methods Female Humans Reproducibility of Results Ribs / diagnostic imaging Tomography
Age estimation Computed tomography Forensic anthropology Sternal rib

Journal

International journal of legal medicine
ISSN: 1437-1596
Titre abrégé: Int J Legal Med
Pays: Germany
ID NLM: 9101456

Informations de publication

Date de publication:
May 2022
Historique:
received: 18 08 2021
accepted: 09 02 2022
pubmed: 2 3 2022
medline: 15 4 2022
entrez: 1 3 2022
Statut: ppublish

Résumé

Age estimation is a key factor for identification procedure in forensic context. Based on anthropological findings, degenerative changes of the sternal extremity of the 4th rib are currently used for age estimation. These have been adapted to post-mortem computed tomography (PMCT). The aim of this study was to validate a post-mortem computed tomography method based on a revision of the Iscan's method on a French sample. A total of 250 PMCT (aged from 18-98 years (IQR 36-68 years, median 51 years); 68 (27%) females) from the Medicolegal Institute of Paris (MLIP) were analyzed by two radiologists. The sternal extremity of 4th right rib was scored using method adapted from Iscan et al. Weighted κ was used to evaluate intra- and inter-observer reliability and Spearman correlation was performed to evaluate relationship between age and score. Confidence intervals for individual prediction of age based on 4th rib score and sex were computed with bootstrapping. The intra-observer reliability and inter-observer reliability were almost perfect (weighted κ = 0.85 [95%CI: 0.78-0.93] and 0.82 [95%CI 0.70-0.96] respectively). We confirmed a high correlation between the 4th rib score and subject age (rho = 0.72, p < 0.001), although the confidence intervals for individual age prediction were large, spanning over several decades. This study confirms the high reliability of Iscan method applied to PMCT for age estimation, although future multimodal age prediction techniques may help reducing the span of confidence intervals for individual age estimation.Trial registration: INDS 0,509,211,020, October 2020, retrospectively registered.

Identifiants

DOI: 10.1007/s00414-022-02798-x PMID: 35230486
pubmed: 35230486
doi: 10.1007/s00414-022-02798-x
pii: 10.1007/s00414-022-02798-x
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

833-839

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Références

Interpol (2018) Disaster victim identification guide. In: Interpol website. https://www.interpol.int/How-we-work/Forensics/Disaster-Victim-Identification-DVI . Accessed 17 Mar 2021
Djurić M, Djonić D, Nikolić S et al (2007) Evaluation of the Suchey-Brooks method for aging skeletons in the Balkans. J Forensic Sci 52:21–23. https://doi.org/10.1111/j.1556-4029.2006.00333.x
doi: 10.1111/j.1556-4029.2006.00333.x pubmed: 17209905
Işcan MY, Loth SR, Wright RK (1984) Age estimation from the rib by phase analysis: white males. J Forensic Sci 29:1094–1104
pubmed: 6502109
Işcan MY, Loth SR, Wright RK (1985) Age estimation from the rib by phase analysis: white females. J Forensic Sci 30:853–863
doi: 10.1520/JFS11050J
İşcan MY, Loth SR, Wright RK (1984) Metamorphosis at the sternal rib end: a new method to estimate age at death in white males. Am J Phys Anthropol 65:147–156. https://doi.org/10.1002/ajpa.1330650206
doi: 10.1002/ajpa.1330650206 pubmed: 6507605
Garvin HM, Passalacqua NV (2012) Current practices by forensic anthropologists in adult skeletal age estimation. J Forensic Sci 57:427–433. https://doi.org/10.1111/j.1556-4029.2011.01979.x
doi: 10.1111/j.1556-4029.2011.01979.x pubmed: 22103300
Stout SD, Dietze WH, Işcan MY, Loth SR (1994) Estimation of age at death using cortical histomorphometry of the sternal end of the fourth rib. J Forensic Sci 39:778–784
doi: 10.1520/JFS13655J
Crowder C, Heinrich J, Stout SD (2012) Rib histomorphometry for adult age estimation. Methods Mol Biol Clifton NJ 915:109–127. https://doi.org/10.1007/978-1-61779-977-8_7
doi: 10.1007/978-1-61779-977-8_7
Stout SD, Paine RR (1992) Brief communication: histological age estimation using rib and clavicle. Am J Phys Anthropol 87:111–115. https://doi.org/10.1002/ajpa.1330870110
doi: 10.1002/ajpa.1330870110 pubmed: 1736669
Fanton L, Gustin M-P, Maujean G et al (2012) Geometric and harmonic study of the aging of the fourth rib. Int J Legal Med 126:685–691. https://doi.org/10.1007/s00414-012-0714-6
doi: 10.1007/s00414-012-0714-6 pubmed: 22592208
Epker BN, Kelin M, Frost HM (1965) Magnitude and location of cortical bone loss in human rib with aging. Clin Orthop 41:198–203
doi: 10.1097/00003086-196500410-00022
Miller EJ, Van der Korst JK, Sokoloff L (1969) Collagen of human articular and costal cartilage. Arthritis Rheum 12(1):21–29. https://doi.org/10.1002/art.1780120105
doi: 10.1002/art.1780120105 pubmed: 5765686
McCormick WF (1980) Mineralization of the costal cartilages as an indicator of age: preliminary observations. J Forensic Sci 25:736–741
doi: 10.1520/JFS11287J
Hartnett KM (2010) Analysis of age-at-death estimation using data from a new, modern autopsy sample, part II: sternal end of the fourth rib. J Forensic Sci 55:1152–1156. https://doi.org/10.1111/j.1556-4029.2010.01415.x
doi: 10.1111/j.1556-4029.2010.01415.x pubmed: 20456580
Yavuz MF, İşcan MY, Çöloğlu AS (1998) Age assessment by rib phase analysis in Turks. Forensic Sci Int 98:47–54. https://doi.org/10.1016/S0379-0738(98)00122-4
doi: 10.1016/S0379-0738(98)00122-4 pubmed: 10036759
Haj Salem N, Aissaoui A, Mesrati MA et al (2014) Age estimation from the sternal end of the fourth rib: a study of the validity of İşcan’s method in Tunisian male population. Leg Med 16:385–389. https://doi.org/10.1016/j.legalmed.2014.06.007
doi: 10.1016/j.legalmed.2014.06.007
Muñoz A, Maestro N, Benito M et al (2018) Sex and age at death estimation from the sternal end of the fourth rib. Does Íşcan’s method really work? Leg Med 31:24–29. https://doi.org/10.1016/j.legalmed.2017.12.002
doi: 10.1016/j.legalmed.2017.12.002
Dedouit F, Savall F, Mokrane F-Z et al (2014) Virtual anthropology and forensic identification using multidetector CT. Br J Radiol 87:20130468. https://doi.org/10.1259/bjr.20130468
doi: 10.1259/bjr.20130468 pubmed: 24234584 pmcid: 4067023
Carballeira Álvarez A, Mancini J, Tuchtan-Torrents L et al (2018) Diagnostic value of unenhanced postmortem computed tomography in the detection of traumatic abdominal injuries. Diagn Interv Imaging 99:397–402. https://doi.org/10.1016/j.diii.2017.12.015
doi: 10.1016/j.diii.2017.12.015 pubmed: 29475777
Norberti TP, Giaconi C et al (2019) State of the art in post-mortem computed tomography: a review of current literature. Virchows Arch 475:139–150. https://doi.org/10.1007/s00428-019-02562-4
doi: 10.1007/s00428-019-02562-4 pubmed: 30937612
Brun CN, Christensen AM, Kravarski M et al (2017) Comparative radiologic identification with standardized single CT images of the paranasal sinuses - evaluation of inter-rater reliability. Forensic Sci Int 280:81–86. https://doi.org/10.1016/j.forsciint.2017.08.029
doi: 10.1016/j.forsciint.2017.08.029 pubmed: 28961444
Hatch GM, Dedouit F, Christensen AM et al (2014) RADid: a pictorial review of radiologic identification using postmortem CT. J Forensic Radiol Imaging 2:52–59. https://doi.org/10.1016/j.jofri.2014.02.039
doi: 10.1016/j.jofri.2014.02.039
Gascho D, Flach PM, Schaerli S et al (2018) Application of 3D image fusion for radiological identification of decedents. J Forensic Radiol Imaging 13:12–16. https://doi.org/10.1016/j.jofri.2018.04.002
doi: 10.1016/j.jofri.2018.04.002
Lottering N, MacGregor DM, Meredith M et al (2013) Evaluation of the Suchey-Brooks method of age estimation in an Australian subpopulation using computed tomography of the pubic symphyseal surface. Am J Phys Anthropol 150:386–399. https://doi.org/10.1002/ajpa.22213
doi: 10.1002/ajpa.22213 pubmed: 23283754
Merritt CE (2018) Part I - Adult skeletal age estimation using CT scans of cadavers: revision of the fourth rib methods. J Forensic Radiol Imaging 14:39–49. https://doi.org/10.1016/j.jofri.2018.08.003
doi: 10.1016/j.jofri.2018.08.003
Blaszkowska M, Flavel A, Franklin D (2019) Validation of the Iscan method in clinical MSCT scans specific to an Australian population. Int J Legal Med 133:1903–1913. https://doi.org/10.1007/s00414-018-01992-0
doi: 10.1007/s00414-018-01992-0 pubmed: 30610446
Grabherr S, Cooper C, Ulrich-Bochsler S et al (2009) Estimation of sex and age of “virtual skeletons” – a feasibility study. Eur Radiol 19:419–429. https://doi.org/10.1007/s00330-008-1155-y
doi: 10.1007/s00330-008-1155-y pubmed: 18766348
Dedouit F, Bindel S, Gainza D et al (2008) Application of the Iscan method to two- and three-dimensional imaging of the sternal end of the right fourth rib. J Forensic Sci 53:288–295. https://doi.org/10.1111/j.1556-4029.2007.00642.x
doi: 10.1111/j.1556-4029.2007.00642.x pubmed: 18284532
Diedenhofen B, Musch J (2015) cocor: a comprehensive solution for the statistical comparison of correlations. PLoS ONE 10:e0121945. https://doi.org/10.1371/journal.pone.0121945
doi: 10.1371/journal.pone.0121945 pubmed: 25835001 pmcid: 4383486
Boldsen JL, Milner GR, Konigsberg LW, Wood JW (2002) Transition analysis: a new method for estimating age from skeletons. In: Hoppa RD, Vaupel JW (eds) Paleodemography, 1st edn. Cambridge University Press, pp 73–106
doi: 10.1017/CBO9780511542428.005
Konigsberg LW, Herrmann NP, Wescott DJ, Kimmerle EH (2008) Estimation and evidence in forensic anthropology: age-at-death. J Forensic Sci 53:541–557. https://doi.org/10.1111/j.1556-4029.2008.00710.x
doi: 10.1111/j.1556-4029.2008.00710.x pubmed: 18471197
Cunha E, Baccino E, Martrille L et al (2009) The problem of aging human remains and living individuals: a review. Forensic Sci Int 193:1–13. https://doi.org/10.1016/j.forsciint.2009.09.008
doi: 10.1016/j.forsciint.2009.09.008 pubmed: 19879075
Anderson MF, Anderson DT, Wescott DJ (2010) Estimation of adult skeletal age-at-death using the Sugeno fuzzy integral. Am J Phys Anthropol 142:30–41. https://doi.org/10.1002/ajpa.21190
doi: 10.1002/ajpa.21190 pubmed: 19845027
Bassed RB, Briggs C, Drummer OH (2011) Age estimation using CT imaging of the third molar tooth, the medial clavicular epiphysis, and the spheno-occipital synchondrosis: a multifactorial approach. Forensic Sci Int 212:273.e1–5. https://doi.org/10.1016/j.forsciint.2011.06.007
doi: 10.1016/j.forsciint.2011.06.007
Bascou A, Dubourg O, Telmon N et al (2021) Age estimation based on computed tomography exploration: a combined method. Int J Leg Med. https://doi.org/10.1007/s00414-021-02666-0
doi: 10.1007/s00414-021-02666-0
Wang G, Hao J, Ma J, Jiang H (2011) A comparative assessment of ensemble learning for credit scoring. Expert Syst Appl 38:223–230. https://doi.org/10.1016/j.eswa.2010.06.048
doi: 10.1016/j.eswa.2010.06.048
Villa C, Buckberry J, Cattaneo C et al (2015) Quantitative analysis of the morphological changes of the pubic symphyseal face and the auricular surface and implications for age at death estimation. J Forensic Sci 60:556–565. https://doi.org/10.1111/1556-4029.12689
doi: 10.1111/1556-4029.12689 pubmed: 25613520
Wink AE (2014) Pubic symphyseal age estimation from three-dimensional reconstructions of pelvic CT scans of live individuals. J Forensic Sci 59:696–702. https://doi.org/10.1111/1556-4029.12369
doi: 10.1111/1556-4029.12369 pubmed: 24502392
Chiba F, Makino Y, Motomura A et al (2013) Age estimation by multidetector CT images of the sagittal suture. Int J Leg Med 127:1005–1011. https://doi.org/10.1007/s00414-013-0883-y
doi: 10.1007/s00414-013-0883-y
Belghith M, Marchand E, Ben Khelil M et al (2021) Age estimation based on the acetabulum using global illumination rendering with computed tomography. Int J Leg Med. https://doi.org/10.1007/s00414-021-02539-6
doi: 10.1007/s00414-021-02539-6
Peng H, Gong W, Beckmann CF et al (2021) Accurate brain age prediction with lightweight deep neural networks. Med Image Anal 68:101871. https://doi.org/10.1016/j.media.2020.101871
doi: 10.1016/j.media.2020.101871 pubmed: 33197716
Cerezo-Román JI, Hernández Espinoza PO (2014) Estimating age at death using the sternal end of the fourth ribs from Mexican males. Forensic Sci Int 236:196.e1-196.e6. https://doi.org/10.1016/j.forsciint.2013.12.044
doi: 10.1016/j.forsciint.2013.12.044

Auteurs

Marie-Edith Richard (ME)

Université de Paris, Paris, France.
Service de Neuroradiologie, GHU Paris Psychiatrie et Neurosciences, 1, Rue Cabanis, 75014, Paris, France.

Tania Delabarde (T)

Université de Paris, UMR8045 BABEL, CNRS, Paris, France.
Institut Médico-Légal de Paris, Paris, France.
Pôle Universitaire d'imagerie Post-Mortem, Université de Paris, Paris, France.

Ghazi Hmeydia (G)

Service de Neuroradiologie, GHU Paris Psychiatrie et Neurosciences, 1, Rue Cabanis, 75014, Paris, France.
Institut de Psychiatrie et de Neurosciences de Paris, INSERM UMR 1266, IMA-BRAIN, Paris, France.

Corentin Provost (C)

Université de Paris, Paris, France.
Service de Neuroradiologie, GHU Paris Psychiatrie et Neurosciences, 1, Rue Cabanis, 75014, Paris, France.
Institut de Psychiatrie et de Neurosciences de Paris, INSERM UMR 1266, IMA-BRAIN, Paris, France.

Laura de Jong (L)

Service de Neuroradiologie, GHU Paris Psychiatrie et Neurosciences, 1, Rue Cabanis, 75014, Paris, France.
Institut de Psychiatrie et de Neurosciences de Paris, INSERM UMR 1266, IMA-BRAIN, Paris, France.

Lilia Hamza (L)

Institut Médico-Légal de Paris, Paris, France.
Pôle Universitaire d'imagerie Post-Mortem, Université de Paris, Paris, France.

Jean-François Meder (JF)

Université de Paris, Paris, France.
Service de Neuroradiologie, GHU Paris Psychiatrie et Neurosciences, 1, Rue Cabanis, 75014, Paris, France.
Institut de Psychiatrie et de Neurosciences de Paris, INSERM UMR 1266, IMA-BRAIN, Paris, France.

Catherine Oppenheim (C)

Université de Paris, Paris, France.
Service de Neuroradiologie, GHU Paris Psychiatrie et Neurosciences, 1, Rue Cabanis, 75014, Paris, France.
Institut de Psychiatrie et de Neurosciences de Paris, INSERM UMR 1266, IMA-BRAIN, Paris, France.

Bertrand Ludes (B)

Université de Paris, UMR8045 BABEL, CNRS, Paris, France.
Institut Médico-Légal de Paris, Paris, France.
Pôle Universitaire d'imagerie Post-Mortem, Université de Paris, Paris, France.

Joseph Benzakoun (J)

Université de Paris, Paris, France. j.benzakoun@ghu-paris.fr.
Service de Neuroradiologie, GHU Paris Psychiatrie et Neurosciences, 1, Rue Cabanis, 75014, Paris, France. j.benzakoun@ghu-paris.fr.
Institut de Psychiatrie et de Neurosciences de Paris, INSERM UMR 1266, IMA-BRAIN, Paris, France. j.benzakoun@ghu-paris.fr.
ORCID: 0000-0002-0733-0104

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Classifications MeSH

questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Radiographie › Détermination de l'âge à partir du squelette › Validation of a post-mortem computed...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Validation of a post-mortem computed...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Méthodologie en recherche épidémiologique › Reproductibilité des résultats › Validation of a post-mortem computed...
questionsmedicales.fr › Appareil locomoteur › Squelette › Cage thoracique › Côtes › Validation of a post-mortem computed...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Validation of a post-mortem computed...