Candida albicans
Candida albicans
biofilm
filamentation
pathogenesis
secretion
trafficking
virulence
Journal
Microbiology spectrum
ISSN: 2165-0497
Titre abrégé: Microbiol Spectr
Pays: United States
ID NLM: 101634614
Informations de publication
Date de publication:
27 04 2022
27 04 2022
Historique:
pubmed:
3
3
2022
medline:
30
4
2022
entrez:
2
3
2022
Statut:
ppublish
Résumé
The role of endocytosis in Candida albicans secretion, filamentation, and virulence remains poorly understood, despite its importance as a fundamental component of intracellular trafficking. Given that secretory mutants display defects in endocytosis, we have focused our attention on endocytic mutants to understand the interconnection between endocytosis and other secretory pathways. Using a reverse-genetic approach based upon CRISPR-Cas9 mediated gene deletion, we studied the functions of the gene
Identifiants
pubmed: 35234488
doi: 10.1128/spectrum.01880-21
pmc: PMC8941917
doi:
Substances chimiques
Clathrin
0
Fungal Proteins
0
Types de publication
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0188021Subventions
Organisme : BLRD VA
ID : I01 BX004128
Pays : United States
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