Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Placental Infection Is Associated With Massive Perivillous Fibrin Deposition at the Maternal-Fetal Interface: A Preliminary Study.


Journal

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
ISSN: 1537-6591
Titre abrégé: Clin Infect Dis
Pays: United States
ID NLM: 9203213

Informations de publication

Date de publication:
24 08 2022
Historique:
received: 09 08 2021
pubmed: 3 3 2022
medline: 30 8 2022
entrez: 2 3 2022
Statut: ppublish

Résumé

We observed an increased frequency of massive perivillous fibrin deposition (MPFD) during the second coronavirus disease 2019 (COVID-19) pandemic wave dominated by the Alpha variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). MPFD associated with 100% reverse transcription polymerase chain reaction (RT-PCR) positivity for SARS-CoV-2 and detection by immunohistochemistry. The Alpha variant was identified in all placentas with MPFD that could be sequenced.

Identifiants

pubmed: 35234854
pii: 6540910
doi: 10.1093/cid/ciac173
pmc: PMC8903432
doi:

Substances chimiques

Fibrin 9001-31-4

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e1176-e1179

Informations de copyright

© The Author(s) 2022. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Auteurs

Esin Kotiloglu-Karaa (E)

Department of Cellular Pathology, The Royal London Hospital, Barts Health, United Kingdom.

Beatrix Kele (B)

Division of Infection, The Royal London Hospital, Barts Health, United Kingdom.

Raghavendran Kulasegaran-Shylini (R)

Division of Infection, The Royal London Hospital, Barts Health, United Kingdom.

Claire E Broad (CE)

Division of Infection, The Royal London Hospital, Barts Health, United Kingdom.

Dola Owoyemi (D)

Division of Infection, The Royal London Hospital, Barts Health, United Kingdom.

Joanne Martin (J)

Blizard Institute, Centre for Genomics and Child Health, Queen Mary University, London, United Kingdom.

Graham MacPhail (G)

Department of Cellular Pathology, The Royal London Hospital, Barts Health, United Kingdom.

Stamatina Iliodromiti (S)

Centre for Women's Health, Institute of Population Health Sciences, Queen Mary University London, United Kingdom.

Anna Riddell (A)

Division of Infection, The Royal London Hospital, Barts Health, United Kingdom.

Eliza Alexander (E)

Division of Infection, The Royal London Hospital, Barts Health, United Kingdom.

Teresa Cutino-Moguel (T)

Division of Infection, The Royal London Hospital, Barts Health, United Kingdom.
Blizard Institute, Centre for Genomics and Child Health, Queen Mary University, London, United Kingdom.

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