Allergic Bronchopulmonary Aspergillosis.
ABPA
ABPM
Aspergillus
Asthma
allergic bronchopulmonary mycosis
cystic fibrosis
Journal
Clinics in chest medicine
ISSN: 1557-8216
Titre abrégé: Clin Chest Med
Pays: United States
ID NLM: 7907612
Informations de publication
Date de publication:
03 2022
03 2022
Historique:
entrez:
3
3
2022
pubmed:
4
3
2022
medline:
6
5
2022
Statut:
ppublish
Résumé
Allergic bronchopulmonary aspergillosis (ABPA) is a complex allergic disorder caused by immune reactions against Aspergillus fumigatus. ABPA most commonly complicates the course of patients with poorly controlled asthma. Patients commonly present with uncontrolled asthma, fleeting pulmonary opacities, and bronchiectasis. Pathogenetically, ABPA is characterized by the persistence of A. fumigatus in the airways and an exaggerated type-2 immune response. The interest in ABPA stems from the fact that bronchiectasis in ABPA can be prevented if the disorder is diagnosed timely and treated appropriately. Herein, we summarize the current concepts in the epidemiology, pathogenesis, diagnosis, and treatment of ABPA.
Identifiants
pubmed: 35236565
pii: S0272-5231(21)01249-1
doi: 10.1016/j.ccm.2021.12.002
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
99-125Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.