Electronic Bone Growth Stimulators for Augmentation of Osteogenesis in

animal bone healing capacitive coupling direct current electrical stimulation in vitro pulsed electromagnet field

Journal

Frontiers in bioengineering and biotechnology
ISSN: 2296-4185
Titre abrégé: Front Bioeng Biotechnol
Pays: Switzerland
ID NLM: 101632513

Informations de publication

Date de publication:
2022
Historique:
received: 12 10 2021
accepted: 17 01 2022
entrez: 3 3 2022
pubmed: 4 3 2022
medline: 4 3 2022
Statut: epublish

Résumé

Since the piezoelectric quality of bone was discovered in 1957, scientists have applied exogenous electrical stimulation for the purpose of healing. Despite the efforts made over the past 60 years, electronic bone growth stimulators are not in common clinical use. Reasons for this include high cost and lack of faith in the efficacy of bone growth stimulators on behalf of clinicians. The purpose of this narrative review is to examine the preclinical body of literature supporting electrical stimulation and its effect on bone properties and elucidate gaps in clinical translation with an emphasis on device specifications and mechanisms of action. When examining these studies, trends become apparent.

Identifiants

pubmed: 35237571
doi: 10.3389/fbioe.2022.793945
pii: 793945
pmc: PMC8882968
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

793945

Informations de copyright

Copyright © 2022 Nicksic, Donnelly, Hesse, Bedi, Verma, Seitz, Shoffstall, Ludwig, Dingle and Poore.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Peter J Nicksic (PJ)

Division of Plastic Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.

D'Andrea T Donnelly (DT)

Division of Plastic Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.

Madison Hesse (M)

Des Moines University School of Medicine and Health Sciences, Des Moines, IA, United States.

Simran Bedi (S)

Division of Plastic Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.
Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States.

Nishant Verma (N)

Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States.
Wisconsin Institute for Translational Neuroengineering (WITNe), Madison, WI, United States.

Allison J Seitz (AJ)

Division of Plastic Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.

Andrew J Shoffstall (AJ)

Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States.

Kip A Ludwig (KA)

Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States.
Wisconsin Institute for Translational Neuroengineering (WITNe), Madison, WI, United States.

Aaron M Dingle (AM)

Division of Plastic Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.

Samuel O Poore (SO)

Division of Plastic Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.

Classifications MeSH