Examining the neural correlates of error awareness in a large fMRI study.
anterior cingulate cortex
error awareness
error-monitoring processes
functional magnetic resonance imaging
insula
Journal
Cerebral cortex (New York, N.Y. : 1991)
ISSN: 1460-2199
Titre abrégé: Cereb Cortex
Pays: United States
ID NLM: 9110718
Informations de publication
Date de publication:
20 12 2022
20 12 2022
Historique:
received:
06
07
2021
revised:
30
01
2022
accepted:
05
02
2022
pubmed:
4
3
2022
medline:
17
1
2023
entrez:
3
3
2022
Statut:
ppublish
Résumé
Goal-directed behavior is dependent upon the ability to detect errors and implement appropriate posterror adjustments. Accordingly, several studies have explored the neural activity underlying error-monitoring processes, identifying the insula cortex as crucial for error awareness and reporting mixed findings with respect to the anterior cingulate cortex (ACC). Variable patterns of activation have previously been attributed to insufficient statistical power. We therefore sought to clarify the neural correlates of error awareness in a large event-related functional magnetic resonance imaging (fMRI) study. Four hundred and two healthy participants undertook the error awareness task, a motor Go/No-Go response inhibition paradigm in which participants were required to indicate their awareness of commission errors. Compared to unaware errors, aware errors were accompanied by significantly greater activity in a network of regions, including the insula cortex, supramarginal gyrus (SMG), and midline structures, such as the ACC and supplementary motor area (SMA). Error awareness activity was related to indices of task performance and dimensional measures of psychopathology in selected regions, including the insula, SMG, and SMA. Taken together, we identified a robust and reliable neural network associated with error awareness.
Identifiants
pubmed: 35238340
pii: 6541535
doi: 10.1093/cercor/bhac077
pmc: PMC9837605
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
458-468Subventions
Organisme : Wellcome Trust
ID : 203139/Z/16/Z
Pays : United Kingdom
Informations de copyright
© The Author(s) 2022. Published by Oxford University Press.
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