Preparation and characterization of nanoemulsions of curcumin and echium oil.
Curcumin
Echium oil
In vitro bioaccessibility
Nanoemulsion
Omega-3 fatty acids
Journal
Heliyon
ISSN: 2405-8440
Titre abrégé: Heliyon
Pays: England
ID NLM: 101672560
Informations de publication
Date de publication:
Feb 2022
Feb 2022
Historique:
received:
21
05
2021
revised:
13
08
2021
accepted:
11
02
2022
entrez:
4
3
2022
pubmed:
5
3
2022
medline:
5
3
2022
Statut:
epublish
Résumé
The search for the plant origin bioactive compounds is increasing over animal origin compounds. Echium oil (EO) contains high amounts of plant based omega-3 fatty acids. Moreover, curcumin addition may increase the release of these omega-3 fatty acids during digestion. The study's objective is to determine the bioaccessibility of curcumin in simulated intestinal digestion conditions and the release behavior of fatty acids of echium oil from nanoemulsions. We prepared curcumin and EO nanoemulsions with a microfluidizer using two different concentrations of surfactant, Tween 80 (5% and 10%). Emulsion stability tests, antioxidant analysis, in vitro oil release and fatty acid composition assays were conducted. Results showed that curcumin-containing nanoemulsions provide higher radical scavenging activity than the EO nanoemulsions. In addition,
Identifiants
pubmed: 35243093
doi: 10.1016/j.heliyon.2022.e08974
pii: S2405-8440(22)00262-6
pmc: PMC8861391
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e08974Informations de copyright
© 2022 The Author(s).
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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