Branch-like enhancement on contrast enhanced MRI is a specific finding of cerebellar lymphoma compared with other pathologies.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
04 03 2022
Historique:
received: 02 09 2021
accepted: 18 02 2022
entrez: 5 3 2022
pubmed: 6 3 2022
medline: 15 4 2022
Statut: epublish

Résumé

Branch-like enhancement (BLE) on contrast-enhanced (CE) magnetic resonance imaging (MRI) was found to be effective in differentiating primary central nervous system lymphoma (PCNSL) from high-grade glioma (HGG) in the cerebellum. However, whether it can be applied to assessments of secondary central nervous system lymphoma (SCNSL), or other cerebellar lesions is unknown. Hence, we retrospectively reviewed cerebellar masses to investigate the use of BLE in differentiating cerebellar lymphoma (CL), both primary and secondary, from other lesions. Two reviewers qualitatively evaluated the presence and degree of BLE on CE-T1 weighted imaging (T1WI). If multiple views were available, we determined the view in which BLE was the most visible. Seventy-five patients with the following pathologies were identified:17 patients with CL, 30 patients with metastasis, 12 patients with hemangioblastoma, 9 patients with HGG, and 7 patients with others. Twelve patients presented with PCNSL and five with SCNSL. Of 17 patients with CL, 15 (88%) had BLE, whereas three (5%) out of 58 patients in the non-CL group showed BLE. In patients who underwent three-dimensional-CE-T1WI, BLE was the most visible on the sagittal image. In conclusion, BLE is a highly specific finding for CL and the sagittal image is important in evaluating this finding.

Identifiants

pubmed: 35246572
doi: 10.1038/s41598-022-07581-x
pii: 10.1038/s41598-022-07581-x
pmc: PMC8897486
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3591

Informations de copyright

© 2022. The Author(s).

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Auteurs

Kota Yokoyama (K)

Department of Diagnostic Radiology, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan. kota1986ky@yahoo.co.jp.

Jun Oyama (J)

Department of Diagnostic Radiology, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Junichi Tsuchiya (J)

Department of Diagnostic Radiology, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Jun Karakama (J)

Department of Neurosurgery, Tokyo Medical and Dental University, Tokyo, Japan.

Kaoru Tamura (K)

Department of Neurosurgery, Tokyo Medical and Dental University, Tokyo, Japan.

Motoki Inaji (M)

Department of Neurosurgery, Tokyo Medical and Dental University, Tokyo, Japan.

Yoji Tanaka (Y)

Department of Neurosurgery, Tokyo Medical and Dental University, Tokyo, Japan.

Daisuke Kobayashi (D)

Department of Pathology, Tokyo Medical and Dental University, Tokyo, Japan.

Taketoshi Maehara (T)

Department of Neurosurgery, Tokyo Medical and Dental University, Tokyo, Japan.

Ukihide Tateishi (U)

Department of Diagnostic Radiology, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

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