Magnetic Resonance Image Guided Focused Ultrasound Thalamotomy. A Single Center Experience With 160 Procedures.

Parkinson's disease (PD) essential tremor (ET) focused ultrasound (FUS) thalamotomy tremor

Journal

Frontiers in neurology
ISSN: 1664-2295
Titre abrégé: Front Neurol
Pays: Switzerland
ID NLM: 101546899

Informations de publication

Date de publication:
2022
Historique:
received: 19 07 2021
accepted: 24 01 2022
entrez: 7 3 2022
pubmed: 8 3 2022
medline: 8 3 2022
Statut: epublish

Résumé

MRgFUS thalamotomy has gained popularity as an FDA approved, non-invasive treatment for patients with Essential Tremor and tremor predominant Parkinson's Disease. We present our initial clinical experience with 160 consecutive cases of MRgFUS thalamotomy and describe the clinical outcomes with long term follow-up. A retrospective chart review of all patients who underwent MRgFUS thalamotomy at our institution was performed. CRST Part A tremor scores were obtained pre-operatively and at each follow-up visit along with an assessment of side effects (SE). All patients had a post-operative MRI within 24 h to determine the location, size, and extent of the MRgFUS lesion. One hundred and sixty unilateral MRgFUS Thalamotomies (Left, MRgFUS thalamotomy is a safe and effective procedure for long term improvement of unilateral tremor symptoms, with the most common side-effects being imbalance and sensory disturbance.

Identifiants

pubmed: 35250802
doi: 10.3389/fneur.2022.743649
pmc: PMC8894664
doi:

Types de publication

Journal Article

Langues

eng

Pagination

743649

Informations de copyright

Copyright © 2022 Lak, Segar, McDannold, White and Cosgrove.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Asad M Lak (AM)

Department of Neurosurgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.

David J Segar (DJ)

Department of Neurosurgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.

Nathan McDannold (N)

Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.

Phillip Jason White (PJ)

Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Department of Chemistry and Physics, Simmons University, Boston, MA, United States.

Garth Rees Cosgrove (GR)

Department of Neurosurgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.

Classifications MeSH